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Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

New effective scar treatments are urgently needed due to the current options' limited success.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Lower SHBG levels may increase the risk of PCOS.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.