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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Transplant success has improved with better immunosuppressive drugs and donor matching.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Ethosomes improve drug delivery through the skin but may have side effects like irritation.

Taiwanese women with PCOS experience different symptoms based on age, with younger women facing more hormone imbalances and older women dealing with more metabolic issues.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

Targeting NCoR1 can help treat heart enlargement and dysfunction.

The conclusion is that 24 weeks of low-dose oral minoxidil is safe for men with hair loss, with no significant changes in heart rate or blood pressure.

Anesthetizing walruses is difficult and risky due to their size and sudden health changes.

High Lipid Accumulation Product levels are linked to more hirsutism in women with Polycystic Ovary Syndrome.

Using minoxidil for hair growth may cause skin lesions in some people, and taking breaks from nitrate patches for angina might worsen symptoms.

Steroid hormones can help treat aging issues and improve health in elderly people.

Genetic risk for PCOS can affect children's growth, metabolism, and development from early life into adulthood.

Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.