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The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.

TSH is usually the only test needed to check thyroid function in primary care.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

Testosterone is crucial for development, growth, and various body functions in mammals.

A hair transplant using hair from the back of the head and pubic area was successful in creating a feminine hairline for a male-to-female transgender person.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.

Hormones control reproduction and are crucial for body balance.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Diuretics can cause serious side effects and should be used carefully.

Excess androgens may cause PCOS, not just be a symptom.

Effective PCOS treatments require targeting specific signaling pathways.

A woman in Sri Lanka was diagnosed with lupus after presenting with protein loss from the gut and other symptoms.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The model and estimator can predict drug exposure in kidney transplant patients well.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Hair shedding is an active process that could be targeted to treat hair loss.

New treatments for male hypogonadism are effective and should be personalized.