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COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

People with Myotonic Dystrophy type 1 are more likely to have certain skin conditions, but not more likely to get skin cancer.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Breadfruit is nutritious and has potential health and medicinal benefits, but is currently underused.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

Coconut oil effectively treats sore gums from new dentures and is safe, affordable, and heals quickly.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Understanding hair surface properties is key for effective hair care products.

Blood type affects COVID-19 infection rates differently in Europe and Africa.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Testosterone therapy increases bone density in older men with low testosterone levels.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.