research Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension
Minoxidil effectively treats severe hypertension, but watch for side effects.
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research Long-Term Treatment of Severe Hypertension with Minoxidil, Propranolol, and Furosemide
Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Minoxidil
Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
research The Investigation of Insulin Resistance and Metabolic Syndrome in Male Patients with Early-Onset Androgenetic Alopecia
Early balding men may have insulin resistance, but lifestyle changes can help.
research Morinda Pubescens J.E. Smith (Morinda Tinctoria Roxb.) Fruit Extract Accelerates Wound Healing in Rats
Morinda pubescens fruit extract helps wounds heal faster in rats.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Women's Midlife Health: Reframing Menopause
The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
research The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers
This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
research Testosterone Implants in Women: Pharmacological Dosing for a Physiologic Effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research A Holistic Approach to Antiaging as an Adjunct to Antiaging Procedures: A Review of the Literature
Combining cosmetic procedures with lifestyle changes improves antiaging results.
research Novel In Vitro Culture Condition Improves the Stemness of Human Dermal Stem/Progenitor Cells
New culture method keeps human skin stem cells more stem-like.
research The G60S Connexin43 Mutant Regulates Hair Growth and Hair Fiber Morphology in a Mouse Model of Human Oculodentodigital Dysplasia
The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.
research How Do We Investigate Hematuria and What Role Has Finasteride?
Finasteride can treat prostatic haematuria, but its use is controversial.
research Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging
Curcumin may help reverse aging by targeting specific genes.
research Synthetic Studies Toward the Development of Novel Minoxidil Analogs and Conjugates with Polyamines
New minoxidil compounds with better water solubility were made, but their full effects and safety need more research.
research Alterations in Transcriptome and Antioxidant Activity of Naturally Aged Mice Exposed to Selenium-Rich Rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research Multiple Minute Digitate Hyperkeratosis
The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.
research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Keratin
Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Scaled Quantum Chemical Studies of the Molecular Structure and Vibrational Spectra of Minoxidil
The analysis shows where minoxidil's atoms are likely to react and describes its electronic transitions and behavior with temperature changes.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research A Hairy Fall: Syncope Resulting from Topical Application of Minoxidil
A man fainted and felt unwell after using a strong hair growth product, but got better when he stopped using it.
research Effects of 5-Alpha Reductase Inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
research Successful Use of Topical Minoxidil in the Treatment of Hypotrichosis Associated with Desmoplakin Mutations
Topical minoxidil helped an 8-year-old boy with a genetic hair disorder grow hair.
research Female Antiandrogens: Significance, Treatment, and Environmental Concerns
Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research Notes From The Editor Emeritus, 2011–2013
Caffeine can stimulate hair growth, but the best dose and frequency for hair loss treatment are still unknown.