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The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Post-bariatric surgery patients often face gastrointestinal issues, fatigue, dry skin, hair loss, and anxiety.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.