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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Testosterone improves mood and thinking skills; finasteride has no effect.

Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Minoxidil effectively treats hair loss, works better for women, and requires consistent use.

Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Arabidopsis collet hairs are good for studying nuclear movement and DNA content increase during growth.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.

Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

Hair analysis can't determine ponies' calcium and phosphorus levels; use soil and feed tests instead.

Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.

The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.

A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.

Minoxidil effectively promotes hair regrowth in younger patients with small balding areas.

The PP2A-B55α protein is essential for brain and skin development in embryos.