research The Protective Effect of the Crosstalk Between Zinc Hair Concentration and Lymphocyte Count: Preliminary Report
Zinc levels and lymphocyte counts might be important in heart disease development.
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research Dermatologic Adverse Effect of Subcutaneous Furosemide Administration in a Cat
A cat developed skin problems from a certain brand of injected water pills, which went away after switching brands.
research Gene Variant in Amish a Clue to Better Aging
A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.
research The Circular RNA circNlgn Mediates Doxorubicin-Induced Cardiac Remodeling and Fibrosis
A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
research A Novel Homozygous Variant in the DSP Gene Underlies the First Case of Non-Syndromic Form of Alopecia
A new gene variant in the DSP gene is linked to a unique type of hair loss.
research Atypical Kawasaki Disease Presenting as Telogen Effluvium in an 11-Year-Old Female
An 11-year-old girl with Kawasaki disease experienced hair loss that improved after treatment.
research Pharmacology and Pharmacokinetics of Minoxidil
Minoxidil treats high blood pressure and side effects can be managed.
research Topically Applied Minoxidil May Cause Fetal Malformation: A Case Report
Minoxidil use during pregnancy may cause fetal harm.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research Case Report: Two Individuals With AEBP1-Related Classical-Like EDS - Further Clinical Characterisation and Description of Novel AEBP1 Variants
The document concludes that individuals with a rare genetic disorder linked to the AEBP1 gene may experience a unique type of hair loss and should be monitored for heart issues.
research The Rotterdam Study: 2016 Objectives and Design Update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research The Rotterdam Study: 2014 Objectives and Design Update
The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
research Use of Silver in the Prevention and Treatment of Infections: A Review
Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.
research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research A Case of Sheehan Syndrome Presenting with Pancytopenia and Dilated Cardiomyopathy: A Rare Combination
A woman with Sheehan syndrome improved with hormone treatment.
research Follicle Hormones
Follicle Stimulating Hormone is important for fertility.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.
research Reporting on Adverse Clinical Events
Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Ingestion of Minoxidil Associated with Elevated Transaminases in the Absence of Ischemic Hepatitis
Minoxidil ingestion can raise liver enzyme levels.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Direct Vasodilators and Sympatholytic Agents
Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
research Metabolic Syndrome – A New Definition and Management Guidelines: A Joint Position Paper by Various Polish Medical Societies
The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
research Large Pericardial Effusion in a Woman in the Second Trimester of Pregnancy
Early surgical intervention and a multidisciplinary approach are crucial for managing complex cardio-obstetric patients.
research Minoxidil Improves Vascular Compliance, Restores Cerebral Blood Flow, and Alters Extracellular Matrix Gene Expression in a Model of Chronic Vascular Stiffness
Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
research Adult Kawasaki's Disease with Myocarditis, Splenomegaly, and Highly Elevated Serum Ferritin Levels
Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.
research Relation of 24-Hour Urinary Aldosterone Levels with Nondipper Blood Pressure Pattern in Normotensive Individuals
Higher aldosterone levels in urine are linked to a nondipper blood pressure pattern in healthy people.
research Androgenic Alopecia Is Associated With Increased Arterial Stiffness in Asymptomatic Young Adults
Hair loss in young adults is linked to harder arteries.
research Effect of Diurnal Blood Pressure on Endothelial Functions in Essential Hypertensive Patients
Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.