59 citations
,
November 2010 in “Circulation Research” This review discusses the potential role of Wnt signaling in aging-related heart diseases and reports no clinical results.
October 2023 in “BMJ Case Reports” This case report describes a man diagnosed with Hoffman syndrome, characterized by muscle hypertrophy and weakness due to severe hypothyroidism, who had an excellent response to thyroid hormone replacement.
75 citations
,
February 2017 in “Aging” This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.
8 citations
,
December 2016 in “Revista Medica De Chile” This article reviews the safety of finasteride by examining existing literature and does not report new findings, highlighting the ongoing controversies regarding its adverse effects.
August 2008 in “Obstetrics & gynecology science” This review discusses the various features, diagnostic challenges, and associated immediate and long-term morbidities of polycystic ovary syndrome, highlighting its significant impact on quality of life and costs, but reports no new clinical results.
September 2024 in “Wound Repair and Regeneration” This study explored the molecular factors behind delayed wound healing in obesity, highlighting that systemic changes like inflammation and collagen deposition alterations contribute to sustained skin inflammation and reduced mechanical resistance.
33 citations
,
January 2001 in “Critical care clinics” This article reviews the roles and synthesis of essential long-chain fatty acids in the body and reports no new research findings; it emphasizes the importance of dietary sources for these lipids.
28 citations
,
July 2017 in “Journal of Endocrinological Investigation” This study suggests that early onset androgenetic alopecia in men may indicate a male PCOS equivalent, possibly leading to higher risks of metabolic and cardiovascular disorders later in life.
13 citations
,
August 2018 in “Journal of Molecular and Cellular Cardiology” This study demonstrated that finasteride treatment reduced cardiac dysfunction and hypertrophic remodeling in mice after myocardial infarction, suggesting potential as a therapeutic strategy for heart failure.
October 2013 in “Journal of the American College of Cardiology” This study found that individuals with a nondipper blood pressure pattern had higher 24-hour urinary aldosterone levels, suggesting a possible link to heart issues.
November 2022 in “Journal of the Endocrine Society” This case study suggests that marijuana use may be associated with low TSH levels without causing thyroid dysfunction in humans.
7 citations
,
November 2024 in “Journal of Inflammation Research” This review discusses the role of the TRPV4 channel in both normal and diseased intestinal functions and suggests that targeting TRPV4 may have clinical significance for treating intestinal diseases due to its involvement in intestinal barrier dysfunction.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” This article discusses the use of direct vasodilators and sympatholytic agents in hypertension management, highlighting their utility in specific cases like refractory hypertension and heart failure, but reports no new clinical results.
17 citations
,
November 2000 in “Journal of the American Pharmaceutical Association” This review discusses the perimenopause, its symptoms, and management options, emphasizing the role of pharmacists in educating and advising women on treatment strategies and preventive health measures, but it reports no new results.
1 citations
,
June 2024 in “Frontiers in Physiology” This bibliometric study analyzed publications on endoplasmic reticulum stress and atherosclerosis, revealing key research areas and emerging trends in the field without reporting new experimental results.
October 2014 in “Transfusion Clinique et Biologique” This review discusses symptoms and syndromes associated with iron deficiency, with or without anemia, but reports no new clinical findings; the authors highlight the potential influence of intestinal factors on iron absorption.
4 citations
,
June 2023 in “Frontiers in Aging” This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.
1 citations
,
February 2023 This study found a high prevalence of thyrotoxicosis among females in Gujranwala, Pakistan, particularly noting typical symptoms such as goiter, sweating, and menstrual irregularities.
July 2025 in “Journal of Clinical Research and Reports” This abstract provides a narrative overview of polycystic ovary syndrome, discussing its symptoms and related health issues, and does not include new research findings.
In this prospective observational study, researchers observed that hyperthyroidism significantly affects cardiac function, often resulting in reversible cardiac changes, with echocardiography playing a crucial role in diagnosis and monitoring.
119 citations
,
June 2005 in “Journal of Molecular and Cellular Cardiology” This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
11 citations
,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.
1 citations
,
January 2018 in “Eastern Journal Of Medicine” In this case report, a 9-year-old girl using topical minoxidil for alopecia experienced a 6-second asystole with syncope, suggesting careful cardiac monitoring may be needed for minoxidil users.
November 2025 in “Scientific Reports” This study found that metabolic dysfunction-associated steatotic liver disease is linked to a higher risk of androgenetic alopecia, especially in women and individuals with certain lifestyle patterns.
9 citations
,
July 2011 in “The Journal of Sexual Medicine” This article examines 5 alpha-reductase inhibitors and their link to persistent sexual dysfunction, but it reports no new clinical findings.
280 citations
,
July 2018 in “Antioxidants” This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.
223 citations
,
December 2010 in “The Journal of Sexual Medicine” This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.
176 citations
,
June 2017 in “Sexual Medicine Reviews” This review discusses the increasing prevalence of erectile dysfunction in young men and emphasizes the importance of identifying specific causes for effective management, reporting no new clinical results.
155 citations
,
March 2006 in “The American Journal of Medicine” This study found that young women with polycystic ovary syndrome have altered endothelial function associated with insulin resistance and lower adiponectin levels.
50 citations
,
March 2017 in “PeerJ” This study found that longer exposure to 5α-reductase inhibitors significantly increased the risk of persistent erectile dysfunction, especially in younger men exposed to finasteride.