research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
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research Madarosis And Facial Keratinaceous Spines
Reducing immunosuppression and using antiviral creams improved the woman's skin condition.
research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Differential Expression of Retinoic Acid-Synthesizing (RALDH) Enzymes During Fetal Development and Organ Differentiation in the Mouse
Different enzymes are active in different parts of developing mouse organs.
research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration
New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
research Environmental Pollution, Oxidative Stress, and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride, and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis, and Aging
Environmental pollutants like glyphosate, fluoride, and electromagnetic fields can cause health problems by damaging mitochondria and affecting metabolism.
research Special Collection on Inward Rectifying Potassium Channels
Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
research Industry Updates from the Field of Stem Cell Research and Regenerative Medicine in December 2019
Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.
research Omenn Syndrome in a 10-Month-Old Male With Athymia and VACTERL Association
A 10-month-old boy with a rare combination of genetic conditions has severe immune deficiency and treatment challenges.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research Direct Vasodilators and Sympatholytic Agents
Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Toxicity of Acanthospermum Hispidum to Mice
Acanthospermum hispidum is toxic to mice, causing death and damage to internal organs.
research The Good, the Bad, and the Ugly Facets of Insulin Resistance
Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research The Protease Corin Regulates Electrolyte Homeostasis in Eccrine Sweat Glands
Corin helps control salt and sweat release in sweat glands.
research Alert to US Physicians: DHEA, Widely Used as an OTC Androgen Supplement, May Exacerbate COVID-19
The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.
research Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway
A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research Forsythiasides: A Review of the Pharmacological Effects
Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.
research Pharmaceutical Care in Transplantation: Current Challenges and Future Opportunities
Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.
research Dihydrotestosterone Induces Arterial Stiffening in Female Mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research The Progress in Bioprinting and Its Potential Impact on Health-Related Quality of Life
Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.
research The Triacylglycerol Synthesis Enzyme DGAT1 Also Catalyzes the Synthesis of Diacylglycerols, Waxes, and Retinyl Esters
DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.
research ERG Induces Androgen Receptor-Mediated Regulation of SOX9 in Prostate Cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.