November 2024 in “Clinical Nutrition Open Science” This study reports that in mesenchymal cells, the effect of resveratrol on cell viability and metabolic enzyme activity varied with dosage and exposure time, with high doses promoting bone differentiation and potentially benefiting mesenchymal cell health and differentiation into osteoblasts.
July 2026 in “Regenerative Biomaterials” This study found that modifying biphasic calcium phosphate/poly(methyl methacrylate) bone cement with human hair keratin improves its hydrophilicity, mechanical properties, and supports bone repair in rats, indicating potential for orthopedic applications.
18 citations
,
January 2013 in “Evidence-based Complementary and Alternative Medicine” In this study, ALR was found to enhance both the proliferation and osteogenic differentiation of mouse bone marrow mesenchymal stem cells, potentially through specific signaling pathways.
16 citations
,
January 2023 in “Regenerative Biomaterials” This study examined 3D-printed scaffolds coated with polydopamine and observed that they significantly enhanced osteogenesis and angiogenesis in vitro and in a rat cranium defect model, suggesting their potential for repairing large bone defects.
11 citations
,
February 2018 in “Medical science monitor” This study found that an alternating inflatable head pad significantly reduced the incidence and severity of occipital pressure ulcers and alopecia in patients undergoing open heart surgery, suggesting improved postoperative nursing and patient quality of life.
8 citations
,
March 2022 in “Frontiers in Cell and Developmental Biology” This study found that intravenous transplantation of human hair follicle-derived mesenchymal stem cells improved trabecular bone mass in osteoporotic mice by enhancing bone formation and reducing bone resorption.
7 citations
,
February 2009 in “Cell and tissue biology” 9 citations
,
August 2025 in “Current Issues in Molecular Biology” This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.
56 citations
,
October 2007 in “Journal of Biological Chemistry” This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.
22 citations
,
October 2004 in “Journal of Investigative Dermatology” This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.
17 citations
,
November 2015 in “Oxidative Medicine and Cellular Longevity” This study suggests that FGF-9 treatment may improve cardiac function by reducing vascular apoptosis and enhancing angiogenesis in infarcted hearts of both nondiabetic and diabetic mice.
4 citations
,
May 2024 in “Biomolecules” This study examined connections between bioelements like Zn, Cu, and Mn in serum and bone tissue and hormone concentrations in men with and without erectile dysfunction, highlighting potential relationships that may help explain ED's etiology.
24 citations
,
February 2021 in “Polymers” This study found that urchin-like Ag–Au bimetallic and Ag nanoparticle-decorated PAN mats showed significant antibacterial effects and potential for wound healing in in vitro and in vivo animal models.
This review discusses the complex process of wound healing and emerging areas of interest in wound treatment, reporting no new clinical findings.
488 citations
,
July 2021 in “Cell” This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.
21 citations
,
September 2015 in “International journal of gynaecology and obstetrics” This article discusses safety, management, and adverse effects of chemotherapy in gynecological malignancies without reporting new clinical data, and emphasizes the importance of thorough patient and drug selection.
5 citations
,
May 2018 in “Therapeutic advances in drug safety” This review discusses the role of androgen therapy and neurosteroids in cerebrovascular health, highlighting the potential risks and benefits and the importance of pharmacogenetic testing, but reports no new experimental results.
161 citations
,
August 2012 in “Seminars in cell & developmental biology” This review discusses the molecular mechanisms involved in hair follicle development and regeneration, highlighting findings from mouse genetic studies, and reports no new experimental results.
400 citations
,
January 2014 in “British Journal of Sports Medicine” This consensus statement discusses guidelines for screening, diagnosing, and treating the Female Athlete Triad, and introduces a risk stratification system to assist healthcare providers with sports participation decisions.
29 citations
,
October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
14 citations
,
June 2009 in “Journal of veterinary internal medicine” This study describes presumed albendazole toxicosis in alpacas, suggesting that repeated doses as low as 19 mg/kg can lead to severe neutropenia, enteropathy, and potentially death in this species.
8 citations
,
October 2022 in “Regenerative Therapy” This review discusses regenerative medicine approaches for treating alopecia, including mesenchymal stem cell therapies and platelet-rich plasma, but reports no new clinical results, emphasizing the need for further study.
8 citations
,
January 2014 in “Journal of Stem Cell Research & Therapy” This review discusses advancements in stem cell therapy for cutaneous radiation syndrome, highlighting the potential of various stem cell sources to improve wound healing and reduce symptoms, but reports no new clinical results.
3 citations
,
March 2024 in “iScience” This study found that long-lived proteins in mice, identified across various tissues, may be linked to neurodegenerative and cardiovascular diseases due to their low renewal rate and increased risk of damage.
3 citations
,
March 2023 in “Life” This review discusses recent findings on wound healing with a focus on adipose tissue biology and obesity, but presents no new clinical results.
January 2020 in “Figshare” In this study, finasteride increased cardiac damage but reduced mutagenic effects in male rats treated with anabolic steroid ND, suggesting variable organ-specific responses to metabolic inhibition.
27 citations
,
March 2008 in “Cell stress & chaperones” This study found that localized administration of heat or certain stress protein inducers effectively prevented chemotherapy-induced hair loss in rodent models without affecting chemotherapy efficacy.
14 citations
,
March 2016 in “Mechanisms of Development” This study found that BNC2 is critical for hair follicle regeneration and other developmental processes, as Bnc2−/− mice exhibit incomplete hair follicle development and developmental defects, and BNC1 cannot substitute for BNC2.
7 citations
,
May 2022 in “PLOS ONE” This study found that Hetian sheep with higher wool density produce more and finer wool, with key genes potentially influencing their wool growth and density.
1 citations
,
December 2023 in “Animals” In this study, researchers observed that the skin quality and hair follicle development of Rex rabbits improved when slaughtered in winter compared to summer, with findings suggesting seasonal regulation via multiple signaling pathways affecting fur characteristics.