316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
48 citations,
May 2015 in “NPJ microgravity” A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
42 citations,
April 2011 in “Annals of Pharmacotherapy” Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.
14 citations,
August 2009 in “Cancer epidemiology” AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
7 citations,
May 2014 in “Clinical practice” Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
6 citations,
October 2018 in “Drug safety - case reports” Alitretinoin may cause irreversible hair curling as a side effect.
3 citations,
July 2021 in “Cutis” New military hair rules for women promote inclusivity and prevent hair damage.
3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
1 citations,
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
1 citations,
December 2016 in “Trichology and cosmetology:” Panax ginseng might help with hair growth and has fewer side effects than synthetic treatments.
Lamivudine might reverse hair graying and needs more research for potential treatments.
19 citations,
July 2018 in “ACS biomaterials science & engineering” Bleaching and combing damage hair's surface and mechanical properties.
3 citations,
January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
2 citations,
April 2018 in “Pediatric dermatology” Elaborate princess hairstyles at a theme park caused hair loss and scalp damage in young girls.
66 citations,
December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
13 citations,
December 2017 in “Journal of Cosmetic and Laser Therapy” Low-level laser therapy can stimulate hair growth more effectively than fake devices, but patient satisfaction is similar for both. Results should be taken with caution due to small study sizes and differences between studies. More research is needed.
Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.
March 2005 in “Journal of the American Academy of Dermatology” Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.
June 2004 in “Dermatologic Surgery” The commentary suggests that using a single-scar technique for hair transplants can give good cosmetic results, but some surgeons hesitate to use it despite ways to address their concerns.
165 citations,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
16 citations,
March 2017 in “Bone Marrow Transplantation” Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.
13 citations,
January 2018 in “BioMed Research International” Scalp involvement is common in pemphigus and can lead to hair loss, with the severity of scalp lesions linked to overall disease severity.
11 citations,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
8 citations,
June 2011 in “Nature Biotechnology” Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.
3 citations,
October 2003 in “Annals of Oncology” A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.
Transplanting beard hair into a scalp wound after hair transplant surgery improves scar appearance and hair keeps its normal traits.
January 1991 in “Journal of Pediatric Health Care” Hair loss in children can be caused by fungal infections, trauma, autoimmune disorders, or stress, and treatments vary depending on the cause.
119 citations,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.
58 citations,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
43 citations,
February 2013 in “Developmental dynamics” Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.