4 citations
,
February 2023 in “Research Reports in Clinical Cardiology” This study found that the ACE gene DD genotype and D allele are linked to an increased risk of hypertensive IHD complications, with dyslipidemia also identified as a significant risk factor for ischemic heart disease.
3 citations
,
January 2019 in “Elsevier eBooks” This article discusses the importance of interpreting laboratory data and performing physical assessments to support pharmacists in clinical decision-making and patient consultations, but reports no new empirical findings.
2 citations
,
July 2024 in “Ibn AL- Haitham Journal For Pure and Applied Science” This study found that PCOS women with COVID-19 had lower ACE2 levels and higher insulin resistance, suggesting increased cardiovascular risk.
2 citations
,
February 2023 in “BMC endocrine disorders” This study found that curcumin lowered fasting blood sugar levels and improved menstruation characteristics in women with polycystic ovary syndrome, but it did not affect other metabolic, hormonal, or hirsutism indices.
1 citations
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July 2021 in “Research Square (Research Square)” This study found that osteoporosis is common among Sudanese postmenopausal women, who also showed an increased risk for cardiovascular disease, emphasizing the need for enhanced public health education and preventive measures.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
October 2025 in “Electronic Theses and Dissertations Repository (University of Pisa)” In this study, baricitinib treatment for severe alopecia areata was well tolerated, with minor metabolic changes and PLR emerging as a sensitive marker of treatment response.
September 2025 in “International Journal For Multidisciplinary Research” This study observed that patients with androgenetic alopecia in a western Indian population had a significantly higher prevalence of metabolic syndrome compared to a matched control group, suggesting that individuals with this type of hair loss may benefit from screening for metabolic syndrome.
July 2025 in “Ecotoxicology and Environmental Safety” This study found that higher levels of lead and molybdenum in hair were associated with an increased risk of dyslipidemia, while there was a significant interaction showing opposing effects of lead and cadmium on dyslipidemia risk among adults in China.
August 2024 in “Skin Research and Technology” This study found that omega-6 and certain LDL cholesterol fractions are risk factors for androgenetic alopecia, suggesting a causal link between these lipid-related metabolites and the condition, which could inform future therapeutic approaches.
June 2023 in “Pharmaceuticals” This review reports that sex-related differences in pharmacological response have been observed in SARS-CoV-2 infection, dyslipidemia, and diabetes mellitus, with implications for treatment strategies; for example, men may respond better to genomic vaccines for SARS-CoV-2, while women may benefit more from certain antiviral medications.
May 2018 in “University Library - University of Saskatchewan (University of Saskatchewan)” This study found that in women with polycystic ovary syndrome, a pulse-based diet was more effective than the TLC diet at improving insulin sensitivity and cardiometabolic risk factors, although both diets improved PCOS-specific health outcomes.
2 citations
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January 2013 in “Hair therapy & transplantation” This article discusses the link between hair loss and metabolic syndrome and emphasizes the need for monitoring these patients for cardiovascular disease risk, but it reports no new trial data.
July 2019 in “International journal of contemporary medical research” This study found that dyslipidemia was more common in male patients with androgenetic alopecia than in controls, particularly among those with severe AGA, suggesting a higher risk of altered serum lipids.
418 citations
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June 2003 in “Endocrine Reviews” This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.
204 citations
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May 2014 in “The Journal of Sexual Medicine” This study concluded that current cross-sex hormone treatments for trans men and trans women are effective with a low risk of side effects in the short term, though they did observe specific clinical changes.
53 citations
,
December 2015 in “JAMA Dermatology” This study found that hirsutism and acanthosis nigricans are the most reliable skin markers for diagnosing polycystic ovary syndrome in women and suggest a need for further evaluation of possible metabolic issues.
28 citations
,
July 2015 in “American Journal of Clinical Dermatology” This study found a higher prevalence of metabolic syndrome in patients with lichen planus, especially those with mucosal involvement, which is associated with increased cardiovascular and diabetes risk.
26 citations
,
June 2016 in “Journal of Reproductive Immunology” This study found that in women with polycystic ovary syndrome, xanthine oxidase activity is a useful marker for oxidative stress and is positively correlated with inflammatory markers and cardiovascular disease risk factors.
24 citations
,
January 2012 in “Journal of Cellular Biochemistry” This study found that C-reactive protein may enhance monocyte adhesion to endothelial cells through NOX-mediated oxidative stress, suggesting a potential mechanism for atherogenesis.
21 citations
,
April 2016 in “International Journal of Dermatology” This study found a significant association between female pattern hair loss and metabolic syndrome in Egyptian women, with waist circumference and hypertension particularly linked to the severity of hair loss.
21 citations
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November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
20 citations
,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.
18 citations
,
July 2019 in “Clinical Endocrinology” The researchers reported that among Mediterranean Sicilian women with PCOS, Phenotype B exhibited the most severe metabolic abnormalities, notably obesity and altered glucose metabolism, whereas Phenotype D showed no such issues.
15 citations
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August 2017 in “Scientific Reports” This study found that young men with early-onset androgenetic alopecia have a worse glycolipid profile and hormone pattern similar to women's PCOS, suggesting a possible male PCOS-equivalent syndrome.
10 citations
,
May 2017 in “PLOS ONE” This study found that serum 25-hydroxyvitamin D was inversely associated with serum ferritin levels in Korean men, positively associated in premenopausal women, and not associated in postmenopausal women.
8 citations
,
April 2019 in “Journal of the Endocrine Society” In this study, long-term normalization of testosterone levels in postmenopausal women with hyperandrogenism did not improve body mass index, glucose, or lipid metabolism.
8 citations
,
October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation” This study found that normal ALT levels in women of reproductive age are linked with metabolic and androgenic abnormalities, suggesting ALT could be used beyond liver disease diagnoses.
7 citations
,
January 2017 in “Journal of Clinical Biochemistry and Nutrition” This study found that vitamin D was positively associated with serum ferritin levels in Korean women without metabolic syndrome, but this association was not observed in those with metabolic syndrome.
7 citations
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January 2016 in “Clinical Hemorheology and Microcirculation” In this study, patients with androgenetic alopecia showed no difference in insulin resistance or prevalence of metabolic syndrome but had higher cardiovascular risk due to increased inflammatory markers and lipoprotein(a) levels.