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Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Obese people have more skin problems like stretch marks and infections, which get worse with higher obesity levels.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Using steroids can increase the risk of heart problems.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Impatiens plants have health-promoting compounds and are used for natural food coloring, but more research is needed to understand their full benefits.