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The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Insulin resistance is linked to larger thyroid volume in patients with polycystic ovary syndrome.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.

A postmenopausal woman's excessive hair growth and hair loss were due to a non-cancerous ovarian condition, treated successfully with surgery.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

A male with aromatase deficiency improved bone health with estradiol treatment.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Bariatric surgery improves skin conditions and metabolism but may cause nutritional deficiencies and hair loss.

A 38-year-old man was diagnosed late with Kearns-Sayre syndrome after being wrongly treated for epilepsy.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Organic selenium may offer better retention and less waste in puppies.

Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.

Many women with postadolescent acne also have hormonal imbalances and are at higher risk for metabolic issues.

Hirsutism and acanthosis nigricans are reliable skin signs of PCOS linked to metabolic issues, while acne is not a reliable marker of the condition.

Women with PCOS often have hirsutism and skin changes, which indicate a need for metabolic health checks.

Low PON1 levels may indicate and predict the severity of hair loss.

The type of PCOS a woman has doesn't strongly predict her skin or metabolic symptoms; obesity is a more important factor.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

Severe hair loss in Chinese men is linked to high blood pressure, while in women, it's linked to larger waist size and cholesterol issues.

Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Taking 100 mg of DHEA daily for 16 weeks did not change metabolic and reproductive health significantly but increased certain ovarian markers with minimal side effects.

Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.

Certain fats in the blood are linked to an increased risk of male pattern baldness.