March 2020 in “Journal of the turkish academy of dermatology” In this study, no significant difference was found in serum triglyceride and HDL cholesterol levels between male patients with androgenetic alopecia and those without.
This study found that finasteride could enhance the stemness of dermal papilla cells, suggesting potential benefits for hair regeneration approaches.
February 2019 in “Journal of Pakistan Association of Dermatology” This study found that abnormal serum lipid levels were prevalent among male patients with androgenetic alopecia, with high triglycerides and low HDL observed frequently.
October 2018 in “International Journal of Research in Dermatology” In this study, androgenetic alopecia patients had a significantly higher prevalence of metabolic syndrome and related metabolic disorders compared to those without the condition.
September 2018 in “Fertility and Sterility” In this study, researchers observed that overweight Taiwanese women with PCOS who carry the HSD3B1 1245C allele have a significantly higher risk of developing androgenic alopecia compared to those with the wild-type allele.
July 2018 in “Journal of Evolution of medical and Dental Sciences” In this study, researchers observed that men with androgenetic alopecia had a higher prevalence of metabolic syndrome compared to those without alopecia, which may warrant early screening for metabolic syndrome to prevent coronary artery disease, despite the study's small sample size.
May 2018 in “Endocrine Abstracts” SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
April 2017 in “Journal of Investigative Dermatology” This study identified altered neurological pathways and potential drug targets involved in androgenetic alopecia, suggesting areas for future research and possible therapies.
December 2013 in “Tehran University Medical Journal TUMS Publications” In this study, no significant relationship was found between androgenetic alopecia and hyperlipidemia, but higher levels of cholesterol, LDL, and triglycerides in AGA patients may suggest an increased risk of coronary heart disease.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.
January 2004 in “Journal of Clinical Dermatology” This study found significant differences in serum total lipid, phospholipid, and triglyceride levels between patients with androgenetic alopecia and those without but no differences in LDL, HDL, or total cholesterol.
45 citations
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June 2012 in “JRSM Cardiovascular Disease” In this study, premature coronary artery disease in Indians under 40 was linked to factors like dyslipidemia, low HDL-C, smoking, and central obesity, with cutaneous markers significantly associated.
22 citations
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February 2008 in “Journal of Neurochemistry” This study found that minoxidil prevents long-term serotonergic toxicity induced by MDMA in rats, primarily by opening mitochondrial KATP channels and involving Akt and MAP kinases in its neuroprotective mechanism.
20 citations
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August 2022 in “Archives of Medical Science” This publication discusses the 2021 ESC Guidelines for the prevention of cardiovascular disease in clinical practice and reports no new results.
16 citations
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January 2016 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that men with early-onset androgenic alopecia had a higher prevalence of metabolic syndrome compared to controls without the condition.
2 citations
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December 2016 in “Clinical and Experimental Obstetrics & Gynecology” This study found that women with PCOS and factors like primary infertility, familial history of type 2 diabetes, and specific lipid profiles tend to have less favorable fertility treatment outcomes.
July 2026 in “Journal of the American Academy of Dermatology” Higher fluence low-level laser therapy effectively promotes hair growth in androgenetic alopecia, with varying effects based on sex.
December 2025 in “Annals of the College of Medicine Mosul/Annals of the College of Medecine” The study found that metformin alone most effectively reduced insulin resistance in Iraqi women with PCOS, but combining metformin with finasteride produced greater improvements in insulin sensitivity markers.
This study found that patients with lichen planopilaris exhibit a higher pro-atherogenic lipid profile and elevated atherogenic indexes, suggesting a need for increased cardiovascular and lipid monitoring in these individuals.
January 2015 in “IP Indian journal of clinical and experimental dermatology” This study found statistically significant associations between female androgenetic alopecia and certain components of metabolic syndrome, such as increased waist circumference and hypertriglyceridemia, in the Kashmiri population.
January 2022 in “Italian journal of dermatology and venereology” This study reported that a natural complex showed good efficacy in improving hair loss in both male and female androgenetic alopecia over six months.
April 2023 in “International journal of medical and biomedical studies” This study observed that among 126 Indian patients with androgenetic alopecia, 29.4% had metabolic syndrome, with higher severity of alopecia correlating with increased prevalence of metabolic syndrome components such as obesity and hypertension, suggesting early screening for metabolic risks could be beneficial.
7 citations
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January 2022 in “Plants” This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.
January 1986 in “Journal of Steroid Biochemistry” Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.
June 2025 in “British Journal of Dermatology” This study investigated premature greying and found lower levels of vitamin D and vitamin B12 in affected individuals compared to controls, associating micronutrient deficiencies with altered hair pigmentation, though no significant link between micronutrient deficiencies and inflammatory markers was observed.
12 citations
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February 2019 in “Developmental Biology” This study found that nerve-mediated HDAC1 expression is necessary for blastema formation and limb regeneration in axolotls, and that inhibiting HDACs delays or inhibits this process.
In this study, human dermal papilla cell-derived extracellular vesicles (hDPC-EVs) were found to reduce skin fibrosis in mice by delivering miRNA-182-5p, which inhibits the TGF-β1 signaling pathway.
9 citations
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August 2018 in “Biomedical dermatology” This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.