This study found that combining intralesional PTX and corticosteroids may enhance treatment outcomes for alopecia areata, with PTX showing better long-term effects compared to corticosteroids alone.
This study reported the case of a 30-year-old man with a bluish-grey scalp nodule that developed over a previously stable hairless plaque, revealing histopathological features consistent with epithelioid cell nests and spindle-shaped dermal melanocytes embedded in collagen.
June 2023 in “QJM: An International Journal of Medicine” This study found that combining fractional CO2 laser treatment with platelet-rich plasma led to a statistically significant improvement in hair regrowth for male androgenetic alopecia, compared to using the laser treatment alone.
June 2023 in “QJM: An International Journal of Medicine” This study found that injecting nanofat into the scalp significantly improved hair density and led to high patient satisfaction among 20 individuals with androgenic alopecia, with minimal side effects, although further research is necessary to refine the technique and confirm these results.
In this study, 30 patients with alopecia areata received intralesional methotrexate injections, resulting in significant hair regrowth and decreased levels of lesional TNF-α after three months, suggesting its effectiveness as a treatment.
June 2023 in “QJM: An International Journal of Medicine” This study found that female pattern hair loss and acute telogen effluvium have distinct trichoscopic and histochemical characteristics, which may aid in their diagnosis and differentiation.
October 2021 in “QJM: An International Journal of Medicine” This study found that patients with alopecia areata had significantly higher serum levels of interleukin-17 compared to healthy controls, suggesting a potential role for IL-17 in the disease's pathogenesis.
In this study on patchy alopecia areata treatment involving 20 patients, TCA (triamcinolone acetonide) injections showed a significantly better response and minimal side effects compared to superficial cryotherapy.
October 2021 in “QJM: An International Journal of Medicine” This study found that four sessions of Intense Pulsed Light treatment significantly improved signs of photodamaged skin in adult female patients, as demonstrated by patient satisfaction and 3D camera assessments.
October 2021 in “QJM: An International Journal of Medicine” This study found increased H2O2 levels and decreased E-cadherin levels in vitiligo patients compared to controls, suggesting oxidative stress and compromised cell adhesion may impact the pigmentary system in vitiligo-affected skin.
October 2021 in “QJM: An International Journal of Medicine” In this study, low serum ferritin levels were significantly associated with premature graying of hair, while no significant difference in vitamin D levels was observed between affected individuals and healthy controls.
October 2021 in “QJM: An International Journal of Medicine” This study demonstrated that decellularization of rat lungs effectively removed cellular material while preserving the 3D extracellular matrix, which may aid future human lung tissue engineering.
March 2020 in “QJM: An International Journal of Medicine” This study found that intradermal minoxidil 5% alone and with intralesional triamcinolone acetonide significantly reduced alopecia areata dermoscopic findings, while standard intralesional corticosteroids remain the main first-line treatment for patchy alopecia with less than 50% scalp involvement.
October 2021 in “QJM: An International Journal of Medicine” This exploratory pilot study found that topical sildenafil and minoxidil both significantly increased hair counts in male patients with androgenic alopecia, with varying effects at different scalp regions.
October 2021 in “QJM: An International Journal of Medicine” This study suggests that altered levels of NRF2 may be important in the development of androgenetic alopecia in men.
October 2021 in “QJM: An International Journal of Medicine” This study concluded that smoking, stress, obesity, family history, exercise, hypertension, and unbalanced diet are significant non-genetic factors associated with androgenetic alopecia in Egyptian males.
October 2021 in “QJM: An International Journal of Medicine” This study found that N-acetyl-cysteine alone or combined with minoxidil improved hair parameters in men with early-onset androgenetic alopecia, with tolerable side effects.
October 2021 in “QJM: An International Journal of Medicine” This study found that injection of adipose-derived adult stem cells improved hair density, thickness, and reduced inflammation in women with female pattern hair loss over 24 weeks.
October 2021 in “QJM: An International Journal of Medicine” This study suggests that platelet-rich plasma injections may improve hair follicle health and promote growth in male albino rats with experimentally induced androgenetic alopecia.
October 2021 in “QJM: An International Journal of Medicine” In this pilot study, treatment with lyophilized platelet derived growth factors showed improvement in women with androgenetic alopecia, suggesting it may be a promising new therapy.
October 2021 in “QJM: An International Journal of Medicine” This study found that altered Nrf2 levels may play a significant role in the development of androgenetic alopecia in men.
March 2020 in “QJM: An International Journal of Medicine” In this study, significant improvements in Androgenetic Alopecia were observed with both PRP and SVF therapies, with SVF showing greater effectiveness in increasing terminal and vellus hair counts.
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April 2022 in “Annals Academy of Medicine Singapore” This review covers the clinical features and heterogeneity of polycystic ovary syndrome and reports no new findings, emphasizing the need for further research on its complex traits and interactions.
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May 1987 in “European Journal of Pediatrics” This study concluded that Buserelin can effectively inhibit gonadal activity in children with central precocious puberty over 18 months, potentially improving final height predictions with prolonged treatment.
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June 2009 in “Current Medical Research and Opinion” In this study, men seeking treatment for male pattern hair loss were highly concerned about their condition and had often attempted self-treatment, but many were dissatisfied with their physician consultations due to unmet expectations and perceived indifference from doctors.
This case study presented by the researchers describes the effective use of topical calcipotriene ointment in treating a 6-year-old girl with en coup de sabre scleroderma, resulting in normalization of the sclerotic skin, hair regrowth, and improved pigmentation.
47 citations
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March 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study identified 43 compounds in Platycladi Cacumen, including flavonoids, and found significant chemical variation in flavonoid content across different regions and processed products.
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December 2023 in “Cutis” This systematic review found that toluidine blue may be valuable for diagnosing and treating specific skin tumors in the context of Mohs micrographic surgery, though literature on its use is limited and mostly qualitative.
September 2024 in “Cureus” This case report describes how changing treatment from adalimumab to guselkumab successfully controlled both pustulotic arthro-osteitis and paradoxical skin reactions in a patient with palmoplantar pustulosis.
September 2019 in “University of Huddersfield Repository (University of Huddersfield)” In this study, nanoemulsion formulations were found to significantly enhance the skin retention of the antiseptic agent triclosan, with the optimal mixture being a low surfactant concentration, as demonstrated through quantitative and qualitative analysis using tape-stripping and micro CT scans.