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This study found that TSC2-null fibroblast cells from TSC skin hamartomas can induce hair follicle formation and hamartomatous changes in keratinocytes, with active mTOR signaling observable in a mouse xenograft model.

This study suggests that skin tumor cells in tuberous sclerosis complex may promote hamartoma morphogenesis by expressing and releasing higher levels of cathepsin B.

This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.

This review examines the interaction between hedgehog and Wnt/β-catenin signalling in hair follicles and basal cell carcinoma, linking Hh pathway inhibition to both tumor regression and alopecia.

The authors concluded that Lrig1-positive stem cells are essential for sebaceous gland formation in mice, as their ablation led to temporary sebaceous gland disappearance without affecting hair growth.

This narrative literature review examined how linking embryonic development with non-genetic skin anomalies can improve diagnostic accuracy, guide prenatal counseling, and enrich dermatology education by revealing specific vulnerabilities in skin morphogenesis and supporting advances in regenerative medicine.

This article proposes a new classification system for cutaneous adnexal cysts based on their origin in the folliculo-sebaceous unit and sweat glands, aiming to clarify their categorization and origins.

This paper discusses the multipotency of cyst cells and proposes that understanding molecular circuits in cyst formation could enable engineering of desired stem cell culture phenotypes, but reports no new experimental outcomes.

This study identified TSC2 as an important regulator of hair follicle morphogenesis and patterning, with Tsc2cKO mice showing altered hair patterns and frequencies compared to controls.

This review discusses the molecular mechanisms involved in hair follicle development and regeneration, highlighting findings from mouse genetic studies, and reports no new experimental results.

In this study, Lrig1-positive stem cells in mouse hair follicles were found to be essential for sebaceous gland formation and maintenance, with their depletion causing a temporary loss of these glands and changes in cellular differentiation.

This study describes a system for generating hair follicles from dissociated cells in mice, suggesting that successful development requires a foundational epithelial platform.

This study found that TGF-β1 expression in follicular tumors correlates with differentiation degree and suggests its potential role alongside p63 in differentiating between sebaceous and follicular tumors.

This review discusses potential cell sources and bioengineering strategies for regenerating hair follicles with functional cycling, reporting no new results.

This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.

This study observed high expression of mTOR pathway effectors in fibrous papules and TSC-associated angiofibromas, suggesting that topical rapamycin might be an effective treatment for fibrous papules.

This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.

This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.

This symposium abstract reports no new experimental results and discusses the pathophysiology of hair growth as presented at an event organized by the Institute of Dermatology.

This study found that hypertrophic chondrocytes at the fracture callus border may convert to osteoblasts, influenced by vasculature and pluripotency gene expression.

This study found that IL-17A-producing γδ T cells play a key role in bone fracture healing by promoting bone formation, with deficiencies leading to impaired repair in mice.

This study demonstrated that cultured human dermal papilla cells can induce full hair follicle formation when combined with neonatal foreskin keratinocytes in a grafted dermal-epidermal construct on mice.

This article discusses the challenges and possible solutions in hair restoration surgery, focusing on donor hair availability, hair survival, and concealing surgical evidence, and reports no new clinical results.

This study found that the patch assay effectively reconstituted mature hair follicles using culture-expanded human fetal cells and may serve as a method to assess cell trichogenicity.

This review discusses the history and challenges of hair follicle regeneration using follicular fragments and dissociated cells, without presenting new clinical results.

This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.

This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.

This review discusses the strategies and progress in developing bioengineered organ replacement therapies but reports no new clinical results, highlighting the potential for future regenerative solutions.

This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.