Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reports that the tetrapeptide AcSDKP significantly promotes skin and hair health in vitro and ex vivo, suggesting it could be used cosmetically to counteract skin aging and hair loss.

This study found that 5α–reductase activity is higher in infrainfundibular keratinocytes compared to interfollicular epidermal keratinocytes, suggesting a potential role in acne-related follicular changes.

This review outlines diagnostic possibilities for diffuse, nonscarring hair loss in women and reports no new clinical findings.

This study found that hair follicle cells' growth in vitro is influenced by the concentration of androgens and antiandrogens, with papilla cells and outer root sheath keratinocytes showing distinct sensitivity.

In this study, minoxidil and human platelet lysate affected gene expression related to hair growth signaling pathways in mouse hair follicle cells.

In this study, oral collagen peptides increased certain gene expressions related to epidermis development and the hair cycle in hairless mice skin, suggesting potential links to hair health.

This study found that β-catenin is essential for hair follicle stem cell proliferation and may regulate this process through the PI3K/Akt pathway, suggesting its potential as a therapeutic target.

This review discusses the potential role of the dietary antioxidant index in reducing the risk of various diseases, including obesity-related conditions, certain cancers, osteoporosis, and mental illnesses, but calls for further studies to confirm these findings.

This study found that brain-derived nerve factor protein expression was significantly increased in balding scalp samples from men with androgenetic alopecia, suggesting it may play a role in hair follicle regulation.

This study found that hydro-alcoholic Eclipta alba extract may have anticancer and multidrug resistance-reversal effects in animal models, suggesting potential as an adjunctive agent in tumor chemotherapy.

This article presents a case of primary adrenal localization of non-Hodgkin's lymphoma in a 70-year-old woman, detailing her diagnosis and treatment, with no signs of recurrent disease after polychemotherapy and radiotherapy.

This study in rats suggests that combining the 5 alpha-reductase inhibitor 4-MA with the antiandrogen Flutamide may enhance prostate cancer therapy by additively inhibiting prostatic growth and mRNA levels of androgen-sensitive prostatic binding proteins.

This study demonstrates that Tp63-expressing epithelial stem cells from non-skin tissues can respond to skin morphogenetic signals and contribute to the formation of hair follicles, sebaceous glands, and epidermis.

This study found that activating the Nrf2 pathway in human mast cells effectively suppresses degranulation and inflammation induced by substance P.

This article proposes a novel hypothesis that androgenetic alopecia may be mainly caused by skull bone expansion affecting blood supply to hair follicles rather than differences in individual follicle programming, and calls for more genetic research into skull development.

Early diagnosis and personalized treatment are crucial for managing different types of alopecia effectively.

This study found that the androgen precursors DHEA and androstenedione stimulated androgen-sensitive parameters in the sebaceous glands of the skin in castrated male hamsters.

This study found that Bazhengsan significantly reduced inflammation and hyperplasia in male rats with nonbacterial prostatitis, indicating potential as a treatment for chronic prostatitis.

In this study, the CYP 21A2 gene p.V281L mutation was associated with an increased susceptibility to familial frontal fibrosing alopecia, suggesting an antigen-driven mechanism linked to certain human leukocyte antigen haplotypes.

This article reviews the increasing incidence of frontal fibrosing alopecia since its first description in 1994 and reports no new results.

This review discusses the confusion and misuse of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea, highlighting their plant origins, uses, and toxicities, without providing new clinical results.

Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.

This hypothesis article explores frontal fibrosing alopecia as a potential autoimmune condition and calls for future research to investigate this possibility, but reports no new clinical results.

In this study, adipose-derived stem cells from human scalp were successfully directed towards chondrocyte differentiation, with TGF-beta3 and BMP-6 growth factors proving effective for in vitro chondrogenesis.

This case report describes a 38-year-old male with scarring body hair loss as the sole manifestation of lichen planopilaris, characterized by progressive alopecia and preceding itching.

In this study, saw palmetto supplements showed varied effects on cell growth in vitro and did not significantly inhibit growth in the hamster flank organ model despite a notable trend.

This study suggests that low proliferation rates in bald areas of androgenetic alopecia patients, along with persistent inflammatory infiltrate, may lead to follicular miniaturization and fibrosis.

This study found that a gene from hamster flank organs is indirectly regulated by androgens, despite lacking direct androgen responsive elements, indicating involvement of androgen-dependent transcription factors.

This review focuses on the roles of amino acids, peptides, and proteins in cosmetics, highlighting their importance in skin health and their potential for development in personal care products due to their unique properties and biocompatibility.

This study found that cortexolone 17α-propionate showed strong topical antiandrogenic activity, outperforming progesterone and several known antiandrogens, but lacked systemic antiandrogenic effects in animal models.