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Understanding skin, hair, and nails is crucial due to their complexity and impact on health.

This study demonstrated that cultured epidermal stem cells and skin-derived precursors can regenerate functional hair follicles and sebaceous glands in both mice and adult humans, suggesting potential for bioengineered skin substitutes.

This study demonstrated that engineered skin substitutes using human keratinocytes and murine dermal papilla cells can develop pigmented hairs without sebaceous glands, suggesting separate pathways for hair development and eruption.

This study describes a protocol for generating hair-bearing skin organoids from human pluripotent stem cells, achieving full complexity resembling fetal skin tissue by day 130 in vitro.

In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.

This study demonstrates that incorporating human neopapilla into reconstructed human skin can initiate hair follicle morphogenesis by stimulating epidermal invagination and maintaining follicle-inductive properties in vitro.

The new system can grow hair in the lab and test hair growth treatments.

This research found that spontaneous and depilation-induced hair growth result in biologically distinct telogen phases in murine skin, with variations in thickness, pigment content, and hair follicle composition.

This case report describes how a combined nude and hair-bearing full-thickness skin graft was used after micrographic surgery to achieve a cosmetically satisfactory reconstruction of a large eyebrow defect.

In this study, neonatal murine skin-derived cells transplanted using a mini-chamber method successfully produced robust and normal hair, contrasting with human scalp follicles which did not achieve follicle reconstruction.

This study found that incorporating hair follicle-primed spheroids into skin constructs showed potential for developing hair-bearing skin mimetics with follicle-forming abilities in vitro.

In this study, researchers developed a relatively simple punch assay for regenerating hair follicles using mouse or human cells, finding efficient hair formation with mouse cells but low efficiency with human cells on reconstituted human skin.

This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.

This source underscores the importance of understanding skin structure and function to comprehend both healthy skin biology and skin disease pathophysiology, highlighting skin's extensive involvement in healthcare due to infections, drug reactions, and diseases like psoriasis.

This review discusses the role of phospholipases in skin and hair health, suggesting that understanding their molecular control could inform new treatments for related conditions, but it presents no new clinical results.

This study presented a new algorithm and camera-based system that successfully reconstruct high-quality, 3D representations of facial hair and underlying skin surfaces even in dense regions like eyebrows.

This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.

This review analyzed the complex interactions within the skin microenvironment that influence hair follicle development and regeneration, exploring its role in hair-related disease treatment and highlighting research challenges and future directions.

This study found that a single instance of acute skin stretching can enhance immune surveillance and improve vaccine delivery by increasing skin permeability and promoting immune cell recruitment without causing tissue damage.

In this clinical study, a vegan collagen builder (VEGCOL™️) was shown to safely and effectively improve hair growth, skin smoothness, wrinkle reduction, and joint pain relief in adults, with enhancements varying by dose over a 60-day period.

This study found that near-infrared LED therapy enhanced ATP synthesis, reduced reactive oxygen species, and promoted collagen production and hair growth more effectively than white LEDs in human skin cells and a photoaging mouse model.

This study found that in healthy adult women, a collagen and antioxidant-rich treatment significantly improved skin elasticity, hydration, texture, and reduced wrinkles and hair fall over 56 days compared to a placebo, indicating its efficacy and safety.

This report highlights that scientific collaborations have led to a rise in publications focused on African skin and hair, which could inform the development of locally tailored products and awareness campaigns.

This study found that Biofield Energy Healing Treatment on a herbal mixture increased hair growth and melanogenesis in mice compared to an untreated group.

This study found that adults with β-thalassemia major had a significantly higher prevalence of skin, hair, and nail disorders compared to healthy controls, influenced by factors like age, gender, and ferritin levels.

The research found that hair follicle–derived cytokines, particularly IL-15 and IL-7, regulate skin-resident memory T cells and their role in both immune homeostasis and lymphoma in the skin.

This study found that the BMP antagonist noggin induces hair growth in postnatal skin by neutralizing BMP4's inhibitory activity, potentially mediated by changes in Shh expression.

This study observed that hair follicle innervation in C57BL/6 mice occurs in sequential stages that closely correlate with the development of hair follicles, indicating an interdependent relationship between neuronal and epithelial morphogenesis.

This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.

In this study, researchers used 3D bioprinting to successfully create engineered skin tissues with hair follicle-like structures, potentially enhancing skin grafts and safety testing for chemical compounds by more closely mimicking natural skin complexity.