5 citations
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February 2023 in “Skin Health and Disease” In this study, the Swedish Hairdex-S was well-received by alopecia areata patients and demonstrated strong psychometric properties and consistency with the original version, supporting its use for patient quality of life evaluation and research.
2 citations
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January 2008 This study found that Turkish women with androgenetic alopecia experienced a significant emotional impact on their quality of life.
23 citations
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August 2018 in “Anais Brasileiros De Dermatologia” This study found that patients with androgenetic alopecia reported more impact on their quality of life in terms of emotions, functioning, and symptoms than those with alopecia areata.
19 citations
,
October 2020 in “Journal der Deutschen Dermatologischen Gesellschaft” This review found that despite varied levels of stigmatization reported in studies, hair loss generally leads to stigmatization and a reduced quality of life, but specific research on this stigma is limited.
15 citations
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January 2018 in “Annals of Dermatology” Wigs significantly improve the well-being of people with severe hair loss.
1 citations
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January 2019 in “Indian Journal of Public Health Research and Development” This study found that androgenic alopecia significantly impairs quality of life among adults, with higher impairment observed in males and those who are employed.
1 citations
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October 2016 in “Journal of medical science and clinical research” This study found that younger male patients with androgenic alopecia experienced greater stigmatization and emotional instability but maintained higher self-assuredness and better overall quality of life compared to older patients.
April 2024 in “International journal of community medicine and public health/International journall of community medicine and public health” In this study, researchers found that female pattern hair loss significantly reduces quality of life, particularly affecting younger women who experience more stigmatization, poorer emotional stability, and higher dermatology life quality index scores compared to older women.
January 2023 in “Dermatologic Therapy” This study demonstrates a significant correlation between anxiety, depression, and reduced quality of life in individuals with androgenetic alopecia.
December 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study found that patients with androgenetic alopecia, especially those who are young, less educated, and single, experience significantly reduced health-related quality of life.
June 2022 in “Plastic and reconstructive surgery. Global open” This study found that platelet-rich plasma treatment significantly improved patients' quality of life and emotional well-being 3-5 months after treatment for hair loss.
January 2023 in “Aesthetic Plastic Surgery” This study found that platelet-rich plasma treatments improved quality of life for patients with pattern hair loss, as measured by decreased HAIRDEX scores in several domains over 3-5 months.
June 2026 in “Clinical and Experimental Dermatology” This review identified various outcome measure instruments for assessing androgenetic alopecia but found inconsistent application across clinical trials, underscoring the need for standardized assessment methods.
28 citations
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March 1973 in “The Journal of Clinical Endocrinology & Metabolism” This study found that hair follicles from balding men show significant metabolic differences compared to those from non-balding individuals, particularly in their ability to process dehydroepiandrosterone.
April 2018 in “Journal of Investigative Dermatology” This study found that dermal white adipose tissue surrounding human hair follicles enhances proliferation, pigmentation, and hair shaft elongation in an ex vivo setting.
22 citations
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April 1972 in “Journal of Steroid Biochemistry” This study observed that male human hair follicles metabolized dehydroepiandrosterone (DHA) more intensively than skin did and found altered DHA metabolism in follicles from balding individuals.
10 citations
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November 2018 in “Developmental Psychobiology” In this study, testosterone and dehydroepiandrosterone in children's hair were strongly correlated, supporting hair as a potential method for measuring these hormones.
February 2019 in “Psychoneuroendocrinology” This study suggests that measuring hair DHEA and testosterone can reliably reflect long-term average hormone levels in women, overcoming daily and menstrual fluctuations seen in salivary hormone assessments.
2 citations
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February 2023 in “International journal of molecular sciences” This study explored a multidimensional approach to examine body hairs' physico-chemical properties, potentially supporting their use over scalp hairs in forensic and intoxication studies.
2 citations
,
January 1975 in “Archives of Dermatological Research” Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
27 citations
,
December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that dexamethasone treatment reduced cell viability and growth factor expression in human dermal papilla cells, suggesting it inhibits hair growth.
41 citations
,
March 1998 in “Archives of Dermatological Research” This study found that androgen metabolism within hair follicles varies significantly between compartments, with dermal papillae showing high 5α-reductase activity, suggesting a key role in androgen-driven hair growth responses.
50 citations
,
March 2001 in “Clinics in dermatology” This paper reviews the complex anatomy and development of human hair and emphasizes the need to understand these processes for interpreting drug incorporation into hair, with no new clinical results reported.
March 1983 in “The Journal of the American Dental Association” February 1990 in “PubMed” This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.
41 citations
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May 2001 in “PubMed” This study proposes a new clinical scoring method for hair density based on hair diameter diversity, which correlates with existing measures and reflects follicle miniaturization in androgenetic alopecia.
This study found that mild skin injuries in rats, especially those dosed with dihydrotachysterol, lead to mineral deposits in hair follicle tissue within 6-12 hours, as confirmed by chemical and X-ray diffraction analyses.
58 citations
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September 2012 in “Dermatologic Clinics” This article reviews current knowledge on the causes, diagnosis, and medical treatments for androgenetic alopecia, particularly in men, and reports no new findings.
1 citations
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May 2019 in “Journal of The European Academy of Dermatology and Venereology” New method, hair distribution width (HDW), improves accuracy in diagnosing androgenetic alopecia (AGA).
April 2017 in “Journal of Investigative Dermatology” This study identified the dermal sheath as a key component of the hair follicle niche, essential for outer root sheath regression during the hair cycle, highlighting its importance in hair follicle support and regulation.