research Learning From Nudity: Lessons From The Nude Phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
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research A Distinct Gene Close to the Hairless Locus on Chromosome 8p Underlies Hereditary Marie Unna Type Hypotrichosis in a German Family
A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.
research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Woolly Antics Between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Gynecologic and Hormonal Comorbidities of Scarring Alopecia: A Retrospective Review
Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.
research Perspectives of Alopecia Behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype
The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
research Emerging Nonmetabolic Functions of Skin Fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Novel Agents for the Treatment of Alopecia
New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
research Can Male-Pattern Baldness Be Prevented? Promising Results from a Study on Treating Male-Pattern Baldness with Oral Finasteride
Finasteride may increase hair growth and prevent baldness in men, but can cause sexual side effects.
research A Review of Herbal Medications for the Treatment of Alopecia
Herbal medications might be safer and more effective for hair loss than synthetic treatments.
research Australasian Society for Dermatology Research Meeting, May 2007
The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.
research First Reboxetine Trial Results Reported
Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
research Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goat Breed
Hexi cashmere goats' hair growth varies by stage, with Hoxc13 linked to hair activity.
research Telomere Dysfunction Impairs Epidermal Stem Cell Specification and Differentiation by Disrupting BMP/pSmad/P63 Signaling
Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
research Androgenetic Alopecia: Overview
AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
research Mechanisms of Tolerance and Potential Therapeutic Interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
research Racial and Gender Influences on Skin Disease
Different races and genders have unique skin and hair issues, requiring specialized care and more research for effective treatment.
research Alopecia Areata: A Review of Disease Pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research Thyroid Hormone Action on Skin
Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research IL-17 Axis Is a Significant Driver of Skin Inflammation in CARD14 Mutant Pityriasis Rubra Pilaris Model Mice
Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
research Potential Therapeutic Uses of Thyroid Hormone
Thyroid hormone may be useful for treating various skin conditions and needs more research.
research Epithelial Stem Cells: Turning Over New Leaves
Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Generation of Tβ4 Knock-In Cashmere Goat Using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.