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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Melatonin affects mouse skin and may regulate skin functions.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.

Different oil products cause varying levels of skin irritation in mice, which could potentially lead to tumors.

Activin A and follistatin control when hair cells develop in mouse ears.

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Burn scars heal abnormally and more research is needed to find better treatments.

Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.

ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.

Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.

The document concludes that cosmetics need biocompatible, eco-friendly ingredients due to aging populations and demand for effective products.

Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Sphinganine can reduce hair loss and improve scalp health.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Lavandula stoechas helps wounds heal faster in diabetic and non-diabetic rats.