September 2020 in “Nature, Environment and Pollution Technology/Nature, environment and pollution technology” This study found that Wistar rats fed with grass extracts from mining areas accumulated trace metals, particularly in the spleen, leading to organ pathology and signs of toxicity.
January 2020 in “Lʹvìvsʹkij medičnij časopis” This review explores modern scientific approaches in using bioelementology to diagnose and treat different forms of alopecia, reporting no new clinical results but identifying gaps needing further research.
29 citations
,
March 2008 in “Postcolonial Studies” The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.
17 citations
,
June 2019 in “The journal of immunology/The Journal of immunology” This study identified a regulatory element necessary for Foxn1 expression specifically in mouse thymic epithelial cells, crucial for thymus development but not affecting hair follicles.
127 citations
,
March 2004 in “Gynecologic oncology” This study concluded that selenium supplementation for ovarian cancer patients during chemotherapy may have several beneficial effects, such as increased antioxidant enzyme activity, reduced chemotherapy-related symptoms, and higher selenium levels in serum and hair.
8 citations
,
January 2017 in “Environmental monitoring and assessment” Hair from different ethnic groups affects soil nutrient release differently.
5 citations
,
December 2024 in “Journal of Cosmetic Dermatology” Vitamin D and zinc may help treat alopecia areata.
4 citations
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January 2021 in “Acta Dermato Venereologica” This study found that patients with frontal fibrosing alopecia had significantly more titanium-containing nanoparticles in their hair compared to healthy controls, suggesting a potential environmental influence.
10 citations
,
August 2023 in “Clinical Nutrition” This study found that exposure to certain elements during pregnancy, measured in maternal hair, was associated with increased risk of gestational diabetes and potential impacts on infant neurodevelopment, with elements like Ta, Re, and Se posing the highest risk for gestational diabetes.
26 citations
,
April 1975 in “Journal of Wildlife Management” This study found that Alaskan moose hair mineral content varied seasonally and by location, with differences in magnesium, copper, and manganese levels linked to winter-killed calves.
December 2024 in “International Journal of Health Sciences and Research” This study describes the case of a 22-year-old female with alopecia areata linked to vitamin D deficiency, highlighting the importance of early diagnosis and management of deficiency to prevent broader health issues.
2 citations
,
January 2013 This review discusses various forensic applications of hair analysis, such as species identification and drug addiction testing, and reports no new study results.
14 citations
,
February 2014 in “Nutrition in Clinical Practice” This A.S.P.E.N. document offers guidance for managing parenteral nutrition shortages, emphasizing alternative routes and careful allocation to prevent deficiencies.
In this study, researchers observed that graded calorie restriction in mice led to changes in stable isotope ratios and elemental content in bone collagen and hair keratin, potentially indicating intensified mobilization of endogenous proteins and altered bone collagen structure with increased dietary stress.
February 2025 in “Animals” This study found that senior dogs fed amino acid-complexed and lysine-glutamic acid-complexed trace minerals had longer, faster-growing hair and increased activity compared to those fed inorganic trace minerals.
2 citations
,
July 2025 in “Analytical Chemistry” This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.
January 2026 in “International Journal of Pharmaceutical Quality Assurance” In this study, researchers observed that patients with Alopecia Areata had significantly lower serum zinc and higher copper levels compared to healthy controls, indicating a disrupted zinc-copper balance that may contribute to the disease's pathogenesis.
April 2019 in “Progress in Crystal Growth and Characterization of Materials” Hair grows like a crystal at a solid-liquid interface without cell division.
May 2024 in “Pakistan Journal of Health Sciences” This study found that people with chronic telogen effluvium had lower hair and serum iron levels and higher serum copper levels compared to healthy controls.
15 citations
,
June 2020 in “Applied Materials Today” This study found that SA-MS hydrogel released Mo4+ ions which promoted healing of disease-impaired wounds by enhancing cell proliferation and angiogenesis, and through its photothermal effects addressed skin cancer-impaired wounds in mice.
1 citations
,
June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a two-month antioxidant treatment significantly improved hair growth in patients with alopecia areata by enhancing antioxidant defenses and correcting trace metal imbalances.
34 citations
,
July 2020 in “American journal of human genetics” This study identified mutations in the SREBF1 gene that impair SREBP1 function, potentially contributing to IFAP syndrome by affecting skin, hair, and eye development.
January 2012 in “Journal of Investigative Dermatology” The document presented various studies on hair and cutaneous development, revealing insights into hair biology and potential therapeutic targets for hair-related conditions. Key findings included the role of stem cells and their niches in hair regeneration, the impact of TACE/ADAM17 depletion on alopecia, and the expression of somatostatin in hair follicles. Research on genetic factors, such as CYLD mutants and P-cadherin, highlighted their importance in hair growth and pigmentation. Studies on hair aging identified genes involved in hair loss in women over 40. Additionally, the potential of keratinocyte precursors from iPS cells for hair follicle regeneration and the effectiveness of a parathyroid hormone analog in reversing chemotherapy-induced alopecia were explored. The document also discussed the role of cholesterol biosynthesis in cicatricial alopecia, the necessity of Wnt signaling for hair follicle initiation, and the effects of ATP-sensitive potassium channel blockers on hair growth. These findings collectively advanced the understanding of hair growth, alopecia treatment, and skin regeneration.
7 citations
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January 2012 This study reported that in the California Ground Squirrel, certain elements bioaccumulate in hair, providing baseline data for environmental health assessments.
This study developed a mathematical model using hair biomarkers (levels of Mg, K, Fe, Al, Cr) to noninvasively predict iron content in Hereford cattle muscle tissue, potentially improving livestock management and meat quality.
34 citations
,
October 2011 in “Pathology Research International” This article reviews potential factors influencing Behçet's disease, like increased neutrophil functions, immunological changes, stress, and hormonal alterations, but it presents no new clinical results.
8 citations
,
January 2020 in “PeerJ” This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
5 citations
,
December 2014 in “Polish Journal of Public Health” This review discusses the mechanisms of zinc transport, its role in human health, and the effects of zinc imbalance, without reporting new results.
December 2024 in “Problems of Biological Medical and Pharmaceutical Chemistry” This study examined the hair ionomic profiles of first-year RUDN University students and found distinct elemental differences between those from the Moscow region and the Middle East, suggesting these profiles may reflect the geographical and climatic conditions of their previous environments.
January 2018 in “Springer eBooks” Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.