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The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

Secondary syphilis in Cali, Colombia, shows high Treponema pallidum presence and challenges in early diagnosis, needing better public health strategies.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Spironolactone may help enlarge a small breast linked to Becker's nevus.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.

Taking Propecia might lead to the development of cataracts.

Multiple eye conditions were studied, highlighting the importance of various imaging methods for diagnosis, the vision side effects of drugs tamoxifen and Propecia, and the usefulness of optical coherence tomography for diagnosing and monitoring macular and retinal diseases.

Tofacitinib and adalimumab are promising treatments for cicatricial alopecia with few side effects.

Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.

Antibiotics often cause skin reactions, making them a major health concern.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.