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High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

More research is needed to understand how testosterone is maintained in adult males.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Women with androgenetic alopecia often have other symptoms of high androgen levels, requiring further hormone testing.

Topical melatonin and brushing did not affect hair regrowth in Siberian Huskies.

Minoxidil, applied on the skin or taken orally, can improve hair growth in kids, but more research is needed due to possible side effects.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Hair loss increases with age; alcohol raises risk, more female partners lowers it.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.