47 citations
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January 2016 in “MethodsX” This study found that while the reproducibility of hair cortisol measurements in captive chimpanzees was high, the fineness of homogenized hair, sample weight, and extraction time influenced absolute cortisol concentrations.
3 citations
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January 2014 This study concluded that a green tea extract hair tonic was stable, promoted more hair growth than 2.5% minoxidil, and did not cause skin irritation.
63 citations
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August 1996 in “Forensic Science International” In this study, bleaching and perming were found to significantly reduce opiate concentrations in both spiked and naturally opiate-positive human hair samples.
8 citations
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October 2022 in “International Journal of Legal Medicine” This study concluded that drug-distribution measurements using micro-segmental hair analysis are effective for drowned bodies, as natural water containing divalent ions prevents drug washout from hair.
May 2023 in “Jurnal farmasi sains dan praktis” In this research on cinnamon and virgin coconut oil hair tonics, F2 and F3 demonstrated stable physical properties and mild irritation potential, while formula 1 remained non-irritating but less stable regarding pH and viscosity.
September 2020 in “Pharmauho/Pharmauho : Jurnal Farmasi, Sains dan Kesehatan” This study concluded that hair tonic formulated with galangal rhizome and Aloe vera extract was stable according to the Indonesian National Standard, showing consistent organoleptic, pH, and viscosity characteristics after stability testing.
4 citations
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October 2017 in “International Journal of Applied Pharmaceutics” This study found that hair tonics with 5% and 10% licorice extract promoted hair growth in rabbits similarly to 2% minoxidil and were generally safe, although they caused mild eye irritation at the 2.5% concentration.
January 2026 in “Journal of Innovative and Creativity (Joecy)” This study investigated hair growth tonics made with celery leaf extract and found that 4% and 9% concentrations maintained better cyclic stability than 14%, supporting their potential use in herbal cosmetic development due to favorable physicochemical stability.
May 2023 in “Jurnal Penelitian Farmasi & Herbal” In this study, researchers developed cucumber-based hair tonics and tested their physical stability, finding them to be homogenous and meet requirements for color and pH, suggesting potential use as a remedy for hair loss.
February 2026 in “PubMed” Rutin may help regrow hair by stabilizing β-catenin and blocking GSK3β.
4 citations
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October 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” This study found that purified wood vinegar may promote hair growth in mice without toxicity, suggesting its potential use in treating baldness or alopecia.
January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this study, researchers developed a hair tonic using shallots (Allium cepa L.) and found that its F2 formulation was as effective as the positive control in promoting hair growth on the 21st day and remained stable over 28 weeks of testing.
December 2022 in “Journal of Tropical Pharmacy and Chemistry” This study evaluated a hair tonic formulated from oil palm leaf extract, finding it demonstrated very strong antioxidant activity and could prevent hair decolorization from sun exposure, with effective concentrations ranging from 25 to 200 ppm.
September 2022 in “KnE medicine” In this study, variations in candle nut oil concentration (5%, 6%, 7%) impacted the characteristics and stability of a hair tonic nanoemulsion, influencing factors like droplet size, pH, and viscosity.
April 2018 in “Journal of Investigative Dermatology” In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.
July 2026 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, hair tonic formulations containing moringa leaf extract and honey were tested for stability and found to remain stable and non-irritating after storage, meeting specific quality standards.
September 2023 in “Jurnal MIPA (edisi elektronik)” This study formulated and evaluated the physical stability of hair tonic preparations using lime extract (Citrus aurantifolia) at varying concentrations. The researchers found that the tonics exhibited good physical stability, as indicated by meeting Indonesian National Standards, even after undergoing temperature cycling tests.
June 2021 in “Journal of Pharmaceutical Care Anwar Medika” This study investigated the physical stability of hair tonic formulations made from ethanol extract of cayenne pepper leaves, finding that formulations with specific concentrations of propylene glycol and ethanol had good physical stability.
26 citations
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September 2018 in “Colloids and Surfaces B: Biointerfaces” This study reported that a novel liposomal formulation, SP-bFGF-SF-LIP, enhanced bFGF stability and skin permeability, significantly improving hair follicle recovery and wound healing in a mouse model.
August 2025 in “International Journal of Applied Pharmaceutics” This study developed a stable nanoemulsion-based hair serum containing M. oleifera seed oil, which maintained its physical characteristics and reduced the oil's sticky texture, making it more suitable for hair loss treatment compared to traditional formulations.
April 2025 in “Jurnal Multidisiplin Dehasen (MUDE)” In this study, a hair tonic containing fragrant pandan leaf extract and virgin coconut oil was formulated and evaluated, with most variations demonstrating physical stability except for one formulation, which showed instability in the specific gravity test.
January 2021 in “Indonesian Journal on Medical Science” This study concluded that a hair tonic combining aloe vera and celery extracts can be formulated, with formula 1 meeting the stability requirements best over a month.
January 2022 in “Healthy Tadulako Journal” This study found no difference in the physical stability of hair tonic preparations made from sansevieria leaves extract, regardless of whether maceration or soxhletation methods were used.
8 citations
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October 2014 in “Journal of analytical toxicology.” This study found that a single application of 'Lye' or 'No-Lye' chemical straighteners significantly reduced drug concentrations in hair samples from both drug-fortified standards and authentic drug users.
September 2017 in “Journal of Investigative Dermatology” This study found that stabilizing HIF1A in hair follicle cells promoted a shift to glycolysis, potentially reducing oxidative stress and promoting hair growth, particularly in balding dermal papilla cells.
April 2019 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles may boost hair growth by enhancing energy production and blood vessel formation.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source provides supplementary materials for the Carnivore Follicular Integrity Framework, a theoretical model proposing that animal-based diets may support hair follicle stability through several biological mechanisms. The materials include definitions, nutrient tables, and mechanistic notes but do not report empirical results.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This record provides supplementary materials for a theoretical model suggesting that animal-based diets may support hair follicle stability through various biological mechanisms, including regenerative peptides and anti-glycation protection.
August 2026 in “Pharmacy Reports” This study found that a nanoemulsion hair spray formula with 25% PEG 400 showed promising physicochemical stability, but further research is needed to assess its colloidal stability and efficacy in hair growth.
December 2015 in “Biomedical and biopharmaceutical research” This study found that hair care formulations containing argan oil were stable and demonstrated better spreadability and texture profiles compared to those without argan oil.