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The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Using PGPR as biofertilizers can improve soil health and plant growth while reducing reliance on synthetic fertilizers.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Certain drugs change freshwater snail shells to a "banana" shape.

Many adults in Porto have acne, but few know or treat it.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.

The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.

Modern wound dressings like hydrocolloids, alginates, and hydrogels improve healing and are cost-effective.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Bioengineered salivary glands in mice can produce saliva when tasting sour or bitter, but have different protein levels and nerve signals compared to natural glands.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.