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A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

Blue light therapy is safe for skin and may protect against UV radiation.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.

Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.

Vitamin D and calcium are important for skin stem cell function and wound healing.

Targeting the actin cytoskeleton could improve skin healing and reduce scarring.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.

Different fibroblasts play key roles in skin healing and scarring.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Increasing regulatory T cells may help treat alopecia areata by reducing autoimmunity and promoting hair growth.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.

New regenerative techniques show promise for improving skin, healing wounds, and growing hair.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Scalp microneedling may improve hair density and thickness for various alopecia types.

Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.

Vorasidenib can cause unusual hair growth.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Wnt signaling is crucial for skin wound healing and reducing scars.