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This study found that collagen sponges with polyglycolic acid fibers support proper skin and hair follicle restructuring, suggesting potential usefulness for hair reconstitution research and clinical applications.

The reinforced collagen sponge helps grow normal hair in mice.

This study found that 5% activated platelet-rich plasma significantly improved cell proliferation and hair-inductive ability of dermal papilla cells in vitro, and promoted hair follicle formation in mice.

This study describes the process of isolating and analyzing multipotent stem cells from mouse hair follicles for potential use in tissue engineering and regenerative medicine.

In this study using a mouse model, the researchers found that platelet-rich plasma significantly increased the number of newly formed hair follicles and decreased the time for hair formation compared to no treatment.

In this study, mixing mouse epithelial and dermal cells was the most successful method for reconstituting hair follicles in mice, with the hair patch assay providing the quickest results.

This study found that cultured human dermal papilla cells formed into three-dimensional spheres have an increased ability to induce hair follicles from mouse epidermal cells compared to two-dimensional cultures.

This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.

This study suggests that the attachment and interaction between dermal papillae and the hair bulb matrix are crucial for normal hair follicle growth and development in vitro.

This study found that epidermal melanocytes can regenerate hair follicles, whereas non-cutaneous or dermal melanocytes cannot, suggesting two distinct melanocyte lineages with potential implications for melanocyte-related diseases.

In this study, researchers developed a new 3D skin equivalent assay using mouse epidermal and dermal cells that successfully regenerated organized hair follicles, outperforming a 2D model in hair follicle orientation and quantity, and enhanced hair growth when Wnt3a was added.

This study demonstrates that Sox2-positive dermal papilla cells specify particular hair follicle types by showing heterogeneity in gene expression and pathway activation in these cells.

This review discusses the role of dermal cells in hair follicle regeneration and morphogenesis and highlights their potential therapeutic implications, but it reports no new empirical findings.

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.

In this study, neonatal murine skin-derived cells transplanted using a mini-chamber method successfully produced robust and normal hair, contrasting with human scalp follicles which did not achieve follicle reconstruction.

This study found that an improved flap model in nude mice significantly reduces the time needed for hair induction compared to the traditional method, likely due to enhanced blood supply at the transplantation sites.

In this study, treatment with human follicular keratinocyte-conditioned media improved the trichogenicity of cultured dermal cells by activating key signalling pathways, suggesting its potential use in cell therapy for hair loss.

This editorial discusses advances in engineering techniques for hair follicle regeneration and highlights future potential but reports no original research findings.

This study found that elevated STAT5 levels are linked to improved hair-inducing capabilities in human dermal papilla cells, and reducing STAT5 impairs hair follicle induction.

This study suggests that using sebaceous glands from rat tail skin samples may effectively capture hair follicle stem cells, potentially aiding skin regenerative medicine when available tissue is limited.

This study developed an efficient method for isolating and enriching multipotent ovine hair follicle stem cells, which may aid in research on the ovine hair cycle and future wool production.

This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.

This study demonstrated that the large molecule versican plays a critical role in hair induction in dermal papilla cells, with potential implications for developing new hair growth treatments.

In this study, researchers reconstituted the face of Bayard, a historical French knight, using cranial characteristics, DNA analyses for skin, eye, and hair traits, and digital analysis of his portrait.

This protocol describes a method for regenerating hair follicles using a bioengineering technique called the Organ Germ Method, but it reports no new clinical results.

This article outlines methods to study the skin and its molecular traits, focusing on interpretation and techniques applicable to mouse models, including diverse assays and approaches like electron microscopy and large-scale lipid analyses.

This study found that the peptide TSN6 increased epidermal thickness and promoted hair follicle formation in dermal–epidermal composites grafted onto nude mice, with TSN6-treated composites showing more hair follicles and retained grafts compared to control groups.

This study found that metformin may promote hair follicle regeneration by enhancing dermal cell activity in an in vitro mouse model, suggesting potential for treating pattern hair loss.

This study standardized a reproducible three-dimensional human skin model for testing skin tumor promoters, using methods that do not require human skin sourcing.

This article reviews methods to enhance epithelial–mesenchymal interactions for hair follicle bioengineering but does not present new experimental results; it emphasizes optimizing combinations for successful regeneration.