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Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Platelet-rich plasma (PRP) is a simple, cost-effective treatment that promotes hair growth and reduces hair loss, with high patient satisfaction.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The document concludes that understanding the anatomical changes of the ageing face is important for effective rejuvenation treatments.

Follicular Unit Transplantation (FUT) can give great results and patient satisfaction when done carefully and by a skilled surgeon.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.

Early surgical treatment for severe facial injuries from high-energy impacts leads to better recovery.

A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.

HGF/SF increases skin melanocytes but doesn't change melanin type or amount.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

Simvastatin/ezetimibe may help some patients with severe alopecia areata regrow hair.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

The surgical technique of scalp advancement and pretrichial brow lift shortens the forehead and lifts brows, is good for women and transgender women with high foreheads, but not recommended for men and has some risks.

Zinc is important for growth and health in animals, plants, and humans, and not having enough can cause various problems.

Eating less and exercising more, with personalized diet plans and realistic goals, can lead to weight loss and better health, but more research is needed for long-term success.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Improved technique for facial surgery hides scars and maintains hairline.

Skin ulcers from interferon may not depend on the amount given.

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

Vitamin B12 improves the health and growth of hair micrografts.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.