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MPA increases cancer spread by boosting Eph A2 activity.

Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Myrtle has various health benefits and potential for medicine development.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

THSG from a Chinese plant helps with aging and related diseases.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

Using neurohormones to control keratin can lead to new skin disease treatments.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

The research shows how a specially structured nanoemulsion delivers vitamins A and E through the skin.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.