November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
April 2021 in “Journal of Investigative Dermatology” Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.
174 citations,
November 2002 in “Expert Reviews in Molecular Medicine” Hair loss needs more research for better treatments.
151 citations,
February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
120 citations,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
86 citations,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
86 citations,
October 2005 in “Experimental Dermatology” The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
81 citations,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
70 citations,
January 2015 in “Journal of Clinical and Diagnostic Research” Hair loss from Telogen Effluvium usually gets better within 6 months after addressing the cause.
65 citations,
February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
51 citations,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
48 citations,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
45 citations,
August 2019 in “Dermatologic Therapy” Hair loss treatments work better with lifestyle changes.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
38 citations,
September 2017 in “Oncologist” Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
29 citations,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
29 citations,
December 1998 in “Seminars in Cutaneous Medicine and Surgery” New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
27 citations,
April 2018 in “Journal of autoimmunity” iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.
27 citations,
April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
25 citations,
August 2017 in “Lasers in Medical Science” Fractional lasers seem effective and safe for treating hair loss, but more research is needed to find the best treatment methods.
22 citations,
December 2017 in “International Journal of Molecular Sciences” Minoxidil boosts hair growth by increasing blood flow and nutrients to hair follicles.
22 citations,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
19 citations,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
17 citations,
August 2018 in “BMC Genomics” The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
17 citations,
December 2004 in “The Journal of Men's Health & Gender” Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.