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The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

White blood cells and their traps can slow down the process of new hair growth after a wound.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Exosome treatment safely increases hair density in male patients with androgenetic alopecia.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Anifrolumab treatment improves quality of life and reduces disease activity and steroid use in SLE patients.

Immune cells are essential for skin regeneration using biomaterial scaffolds.

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Both cell and non-cell parts are important for rat whisker follicle regrowth.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Not getting enough minerals can lead to health problems and shorter lifespans.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

BMP signaling is essential for the development of touch domes.

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Smart biomaterials that guide tissue repair are key for future medical treatments.

NFIC helps human dental stem cells grow and become tooth-like cells.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

Oral vitamin D treatment can help some children with alopecia areata who have vitamin D deficiency.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.