118 citations,
January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
91 citations,
February 2009 in “Journal of biological chemistry/The Journal of biological chemistry” DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
47 citations,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
28 citations,
October 2004 in “Differentiation” A gene deletion causes the "hairless" trait in Iffa Credo rats.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
20 citations,
September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
19 citations,
January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
10 citations,
January 2014 in “BioMed research international” Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.
5 citations,
January 2006 in “Journal of veterinary medical science” RNA can be extracted from horsehair roots for analysis.
5 citations,
January 2016 in “Journal of Molecular Histology” Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
3 citations,
July 2023 in “International journal of molecular sciences” Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
3 citations,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
2 citations,
May 2023 in “Marine Drugs” Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
2 citations,
December 2022 in “PNAS nexus” SCD-153 shows promise as an effective topical treatment for alopecia areata.
1 citations,
January 2015 in “Journal of nutrition & health” Fish oil improves skin health in people with diabetes and high cholesterol.
The trial aims to understand how obesity and lifestyle affect circadian rhythms in people with schizophrenia and bipolar disorder.
April 2024 in “Cell death and differentiation” Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
April 2024 in “Cosmetics” Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.
February 2024 in “Skin Research and Technology” Microneedle therapy combined with serum effectively increases hair count in people with hair loss, with no side effects.
September 2023 in “Medicine” Herbal extract spray improved hair growth in a man with hair loss.
January 2020 in “대한피부과학회지” Dutasteride effectively increases hair density in women with hair loss.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
November 2022 in “Clinical, Cosmetic and Investigational Dermatology” The combined treatment for hair loss is effective, easy to use, and has mild side effects.
November 2021 in “Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo” Microneedling with minoxidil, platelet-rich plasma, and mesotherapy improves hair growth significantly.
91 citations,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
March 2022 in “International Journal of Trichology” Tofacitinib may be effective for treating hair loss caused by alopecia areata that doesn't respond to other treatments.
5 citations,
April 2015 in “HSOA journal of clinical dermatology & therapy” Triamcinolone acetonide mesotherapy may be effective for treating patchy hair loss in alopecia areata.