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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.

Middle Eastern patients with epidermolysis bullosa show specific genetic mutations linked to different types of the disease.

Different rheumatological diseases can cause specific skin problems.

Macroalgae compounds offer sustainable, effective benefits for cosmetics.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Some nutraceuticals may help in COVID-19 prevention and treatment, but more research is needed.

Piezoelectric Nanogenerators are promising for non-invasive health monitoring but need efficiency and durability improvements.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Deep eutectic solvents are eco-friendly and effective for extracting useful pharmaceutical compounds.

The UK's EDS National Diagnostic Service found that early diagnosis, lifestyle advice, and regular check-ups are crucial for managing vascular Ehlers-Danlos syndrome. A combination of losartan and bisoprolol can reduce vascular events, improving survival and quality of life.

Topical ceramide treatment partially improves the skin condition in Jack Russell Terriers with a genetic skin disorder.

Most skin issues were due to COVID-19, with some caused by vaccines or treatments, and were categorized into five types.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.

Skin aging can be slowed down with proper care and treatments.

Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

Hair transplantation between identical twins can successfully treat severe, nonprogressive hair loss due to follicular aplasia.

Hair loss and excessive growth treated with various options, including new laser technology.

No single biomarker is reliable enough for diagnosing and assessing SLE.