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This study identified a novel microscopic "arrow sign" in hair root sheaths of patients on EGFR inhibitors, potentially aiding in diagnosing related hair changes and differentiating from fungal infections.

This study found that careful light microscopy using fluid-mounted hair improves detection of the pili annulati phenotype, which varies widely in expression and affects hair fragility.

This report describes a 1949 case of a young girl with a rare congenital ectodermal defect causing unique hair fragility, which had not been previously documented in the literature.

This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.

This review discusses the role of keratins in providing mechanical resilience to epithelial tissues and highlights recent therapeutic approaches for keratin diseases, but reports no new experimental findings.

This study mapped monilethrix, a hereditary hair and nail disorder, to the type II keratin cluster on chromosome 12q, marking the first primary human hair disorder localization and implicating defects in "hard" keratins.

A missing mK6irs1 gene causes hair loss in mice.

This study describes a co-dominant E410D mutation in keratin hHb6 associated with severe hair loss and extensive papules in homozygous individuals, with variable expression in heterozygous family members.

The authors reported a possible association between the use of etanercept and the development of trichorrhexis nodosa, a hair shaft disorder, in a patient without apparent external causes.

This case report describes a rare autosomal dominant hair shaft disorder, monilethrix, observed in three consecutive generations of a family, with gradual improvement noted with age.

Frequent hairdryer use may worsen hair fragility in people with Pili Annulati.

This review discusses the potential risks and effects of chemical relaxers on hair and scalp health, reporting no new clinical results; the authors emphasize dermatologist guidance to mitigate these issues.

In this study, researchers identified an autosomal dominant mutation (E402K) in exon 7 of the KRT86 gene as a cause of Monilethrix in a large family from Turkey.

This case report describes the diagnosis of monilethrix in a 2-year-old boy using trichoscopy, highlighting its rarity and the challenge of diagnosing it without a family history.

This study found that the p.E402K mutation in the KRT86 gene is a hotspot in Chinese patients with monilethrix, and treatment with 5% topical minoxidil significantly improved hair density and quality.

This case report describes trichothiodystrophy in two sisters with only hair fragility, illustrating the condition's variable presentation and the importance of regular monitoring for potential associated impairments.

This study observed that chronic kidney disease patients undergoing hemodialysis frequently experience dermatologic manifestations, with xerosis and white nail being the most common skin and nail changes noted in 74% and 56% of patients, respectively.

This study found that VEGF-deficient keratinocytes can form tumors using different aneuploidy and signaling patterns, highlighting VEGF's role beyond angiogenesis in tumor cell growth and survival.

In this case report, a 38-year-old woman with monilethrix, a hair shaft disorder, was found to have both hair fragility and androgenetic alopecia, highlighting the diagnostic and management challenges posed by coexisting hair conditions.

This case report describes a patient who experienced proton-induced alopecia after proton therapy for a frontal meningioma, which was effectively treated with topical minoxidil, resulting in full hair regrowth after 4 months.

This article reports on a family with six members diagnosed with monilethrix, highlighting varying degrees of alopecia linked to this rare hair shaft defect.

This case report describes an eight-year-old Kashmiri boy diagnosed with monilethrix, a rare genetic hair disorder, characterized by a beaded appearance and fragility of the hair shaft.

This case report describes a young girl with trichothiodystrophy and suggests the need for early diagnosis and multidisciplinary interventions for her educational challenges.

This study identified two novel point mutations in the hHb6 gene associated with monilethrix, suggesting these mutations could serve as diagnostic markers for this genetic hair disorder.

Oral minoxidil may help improve fragile hair.

This review outlines the genetic basis of GABEB, highlighting reduced type XVII collagen as a distinguishing marker from Herlitz JEB, and discusses potential therapeutic avenues without presenting new results.

This article outlines the technical aspects, benefits, and challenges of follicular unit extraction for hair transplantation, but it reports no new clinical findings.

This study found that levels of the protein MAGP-1, important for skin elasticity, decrease with aging and photoexposure, potentially contributing to skin fragility, sagging, and enlarged pores.

This review examines nonmalignant skin toxicities from immunosuppressive and transplant-related medications, emphasizing the need for effective identification and management by care providers; it presents no new research findings.

This article reviews the characteristics, causes, and types of porphyria cutanea tarda but presents no new findings, focusing instead on existing knowledge about the disorder.