43 citations
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August 2008 in “Regenerative Medicine” In this study, murine follicular cell aggregates developed into hair-like structures in culture, which upon implantation into mice skin matured into complete hair follicles, suggesting potential for treating hair loss.
27 citations
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September 1988 in “PubMed” In this study, researchers used three-dimensional reconstruction to show that the shape of the hair follicle determines the hair's form, with variations observed among different racial groups.
9 citations
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January 2009 in “International Journal of PharmTech Research” This study found that a herbal oil formulation containing Eclipta alba, Hibiscus rosa sinensis, and Nardostachys jatamansi showed better hair growth effects in wister albino rats compared to 2% minoxidil.
8 citations
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February 2014 in “Stem cells translational medicine” This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.
2 citations
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October 2023 in “Philosophical transactions - Royal Society. Biological sciences” This article reports that mutations in the PADI3 gene, affecting its activity or localization, cause uncombable hair syndrome and are linked to central centrifugal cicatricial alopecia, particularly among women of African ancestry.
2 citations
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February 2021 in “FEBS open bio” In this study, transfection experiments showed that mutations in the K85 gene affect filament formation with K35, which may impact hair formation related to ectodermal dysplasia.
January 1961 in “The Journal of Anthropological Society of Nippon” This study examined hair from a mixed-heritage family and suggested that variations in pigment formation significantly influence hair form, including the occurrence of twist-knots.
June 2026 in “International Journal of Ayurvedic Medicine (Hyderabad)” This study found that Asthimajjapachak Churna provided significantly more therapeutic relief from hair fall than Shwadamshtradi Rasayana Churna in young females over 30 days.
January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that GDNF promotes hair formation and wound repair in mice by enhancing the function of bulge stem cells.
102 citations
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February 2008 in “The FASEB Journal” This study found that human hair follicles express ATP-sensitive potassium channels, suggesting that minoxidil acts on these channels and that drugs targeting them may treat hair disorders.
75 citations
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August 2011 in “Journal of Investigative Dermatology” This study found that cultured human dermal papilla cells formed into three-dimensional spheres have an increased ability to induce hair follicles from mouse epidermal cells compared to two-dimensional cultures.
34 citations
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August 1966 in “Experimental cell research” This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.
22 citations
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December 2013 in “Molecular biology of the cell” This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.
2 citations
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February 2021 in “Case reports in dermatological medicine” In this case series, the topical botanical formulation GASHEE demonstrated significant improvements in hair regrowth without adverse events among patients with hair loss, including cases where previous treatments had failed.
May 2026 in “Iconic Research and Engineering Journals” This review concluded that polyherbal hair oils, using key medicinal plants, may offer a validated and sustainable alternative to synthetic cosmetics for hair and scalp health, with potential for industrial standardization and clinical use.
September 2025 in “Journal of Surfactants and Detergents” In this study, shampoos containing sodium lauroyl methylaminopropionate showed superior coacervate formation and lubrication on wet hair, outperforming other amino acid surfactants and suggesting potential for creating low-irritation, high-performance hair products.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated herbal hair oils formulated with traditional medicinal plants and reported that systematic formulation and testing are crucial for their standardization, quality assurance, and validating their safety and effectiveness as alternatives to synthetic hair products.
January 2026 in “International journal of research and scientific innovation” In this laboratory study, researchers developed a multifunctional organic hair cream with various natural extracts, finding that the cream with 15% extracts demonstrated higher physical stability, hair strength, and antimicrobial activity compared to lower concentration samples and synthetic alternatives.
May 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review discusses how the butterfly pea flower's phytochemicals, such as polyacylated anthocyanins, can improve hair-care product formulations by offering antioxidant, anti-inflammatory, and pigmenting benefits, while also incorporating insights from hair-biology models and organoids to enhance understanding of its effects on hair follicle physiology.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” This study concluded that the optimum biotin microemulsion hair tonic composition involves span 80 (20%), tween 80 (9.47%), and PEG 400 (5%), providing favorable viscosity and globule size.
January 2019 in “Prosiding Program Kreativitas Mahasiswa” This study found that a 15% Pisum sativum extract concentration in hair tonic showed the most effective hair growth, with a length of 14.51mm and weight of 0.16g.
January 2011 in “The Chinese Journal of Dermatovenereology” In this study, DPC-hTERT cells were shown to induce hair follicle-like structures expressing specific keratin when co-injected with epithelial cells into nude mice.
Hair coloring and bleaching can permanently break down hair protein and temporarily change its properties.
67 citations
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May 2007 in “Journal of Cosmetic Dermatology” This study found that topical formulations including extracts from Cuscuta reflexa, Citrullus colocynthis, and Eclipta alba significantly accelerated hair growth initiation and completion in rats, indicating potential benefits for treating alopecia.
13 citations
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September 2020 in “Sensors” This study used melamine formaldehyde particles to measure a pH gradient along the hair shaft, showing a significant pH decrease from the hair sheath to the external shaft.
3 citations
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January 2011 in “Journal of biologically active products from nature” This study found that the polyherbal formulation F1, containing five traditional herbs, significantly enhanced hair growth in terms of length and thickness, suggesting potential for alopecia treatment.
1 citations
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May 2019 in “International Journal of Applied Pharmaceutics” This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
August 2025 in “Journal of Industrial and Engineering Chemistry” A new topical finasteride formulation effectively promotes hair growth with fewer side effects.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers formulated and evaluated an herbal hair smoothing cream containing natural ingredients like aloe vera and coconut oil, reporting significant improvements in hair smoothness, softness, shine, and manageability without irritation, suggesting it as a safer alternative to traditional hair straightening products.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a formulated herbal hair smoothing cream using ingredients like aloe vera and coconut oil improved hair texture, such as smoothness and shine, without irritation, offering a safer alternative to conventional products.