11 citations,
January 1997 in “Skin Pharmacology and Physiology” A certain inhibitor can slow down the decrease in DNA creation in mouse hair follicles, which might help with hair growth.
10 citations,
June 2017 in “Experimental Dermatology” New hair loss treatments have evolved from understanding hair biology and patient needs.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
8 citations,
February 2017 in “Archives of Dermatological Research” Intense pulsed light treatment effectively reduces underarm hair by making hair follicles smaller and extending their resting phase.
6 citations,
December 2021 in “Scientific Reports” Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
2 citations,
October 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
June 2023 in “Journal of cosmetic medicine” Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.
135 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
128 citations,
March 2006 in “American Journal of Pathology” Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
51 citations,
August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
30 citations,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
25 citations,
August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
20 citations,
January 2015 in “Current problems in dermatology” Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
14 citations,
January 2015 in “Genetics and molecular research” The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
10 citations,
January 2016 in “PLOS ONE” Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
10 citations,
April 2013 in “Journal of Investigative Dermatology” Scientists created a model using sheep cells to study hair root formation, which can test how different substances affect hair growth.
9 citations,
July 2011 in “Scientific Reports” Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
6 citations,
November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
5 citations,
December 2020 in “Experimental dermatology” A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
2 citations,
January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
1 citations,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Rhamnose may help hair growth and pigmentation, making it a potential treatment for hair loss.
December 2024 in “Frontiers in Veterinary Science” Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.
April 2024 in “Frontiers in physiology” Immune cells are crucial for hair growth and preventing hair loss.