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    Glossary Hair Follicle-Derived Keratinocytes

    specialized cells from hair follicles producing keratin protein

    Hair Follicle-Derived Keratinocytes are specialized cells that originate from the hair follicle and are responsible for producing keratin, a key structural protein in hair, skin, and nails. These cells play a crucial role in hair growth and regeneration, making them important in studies related to hair loss and skin repair.

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    1. Establishment of a new three‐dimensional human epidermal model reconstructed from plucked hair follicle‐derived keratinocytes Experimental Dermatology · 2016 · 12 citations
    2. Influence of Human Placenta Extracts on Prostanoids Production in Cultured Hair Follicle-Derived Keratinocytes: The Possibility of Pharmaceutical Regenerative Medicine Journal of St. Marianna University · 2020
    3. LB788 Development of a novel three-dimensional human epidermal model from plucked hair follicle-derived keratinocytes 2016
    4. Recovery effects of active oxygen scavengers on murine hair follicle-derived keratinocyte proliferation suppressed by androgen Journal of dermatological science · 1994
    5. Characterization of response of murine hair follicle-derived keratinocyte against androgen and testosterone 5α-redactase activity Journal of dermatological science · 1994
    6. Induced pluripotent stem cell line MUSIi006-A derived from hair follicle keratinocytes as a non-invasive somatic cell source Stem cell research · 2018 · 7 citations
    7. 1435 Enzymatic digestion of scalp hair follicle bulge allows to have more bulge-derived stem keratinocytes than explant isolation 2023
    8. Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation International journal of oncology · 2009 · 8 citations
    9. Anti-Hair Loss Activity of Healthy Human Scalp-Derived Staphylococcus capitis KMH304 Ferment Filtrate in Human Hair-Follicle Dermal Papilla and Keratinocyte Cells Microorganisms · 2026
    10. Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers Journal of Biomaterials Science Polymer Edition · 2020 · 11 citations
    11. An osteopontin‐derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor‐7 production in outer root sheath keratinocytes British Journal of Dermatology · 2019 · 19 citations
    12. Hair follicle-derived epithelial sheet has potential in vitiligo treatment medRxiv · 2026
    13. Exosomes derived from uMSCs promote hair regrowth in alopecia areata through accelerating human hair follicular keratinocyte proliferation and migration Cell Biology International · 2023
    14. 573 Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Generate Diverse Effects on Stem Cells and Progeny in Human Scalp Hair Follicles Ex Vivo Journal of Investigative Dermatology · 2022
    15. Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
    16. Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion Nutrients · 2021 · 9 citations
    17. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    18. ESDR573 - Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Generate Diverse Effects on Stem Cells and Progeny in Human Scalp Hair Follicles Ex Vivo 2022
    19. 621 An apple stem cell-derived extract increases epithelial stem cells number in the hair follicle bulge Journal of Investigative Dermatology · 2019
    20. Ovine Hair Follicle Stem Cells Derived from Single Vibrissae Reconstitute Haired Skin International Journal of Molecular Sciences · 2015 · 18 citations
    21. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients Molecular psychiatry · 2013 · 198 citations
    22. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo 2013 · 64 citations
    23. 857 Human hair follicle regeneration with trichogenic human dermal papilla precursor cells derived from induced pluripotent stem cells Journal of Investigative Dermatology · 2017
    24. Protective Effect of Polysaccharide Derived from Natural Extract on Human Follicle Dermal Papilla Cell and Keratinocytes 2022
    25. The potential role of fibroblast‐derived multi‐peptide factors in activation of growth factors and β‐Catenin in hair follicle cells Journal of Cosmetic Dermatology · 2022 · 4 citations
    26. Bulge-Derived Epithelial Cells Isolated from Human Hair Follicles Using Enzymatic Digestion or Explants Result in Comparable Tissue-Engineered Skin International Journal of Molecular Sciences · 2025 · 1 citations
    27. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    28. The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation Cell transplantation · 2021 · 4 citations
    29. Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle Experimental Dermatology · 2003 · 55 citations
    30. Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion Biomedical research · 2010 · 134 citations