research PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
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research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine
Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
research Genetic Analysis of a Novel Antioxidant Multi-Target Iron Chelator, M30, Protecting Against Chemotherapy-Induced Alopecia in Mice
M30 is a promising treatment for preventing hair loss during chemotherapy.
research Pathogenesis and Causes of Hirsutism
Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
research Direct Cellular Reprogramming Enables Development of Viral T Antigen-Driven Merkel Cell Carcinoma in Mice
Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Vitamin D Receptor, UVR, and Skin Cancer: A Potential Protective Mechanism
Vitamin D receptor may help protect against UV-induced skin cancer.
research Massive Squamous Cell Carcinoma Arising From Hidradenitis Suppurativa With Marked Hypercalcemia and Neutrophilia
A woman with a long-term skin condition developed a serious skin cancer that led to her death.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.
research Conversion of C57Bl/6 Mice from a Tumor Promotion-Resistant to a Sensitive Phenotype by Enhanced Ornithine Decarboxylase Expression
Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
research Hair Loss in Elderly Women: A Dermatological Concern
Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.
research Mommy, Where Do Tumors Come From? The Origins of Basal Cell Carcinomas
Some skin tumors may start from hair follicle stem cells.
research Hair Follicle Regeneration Suppresses Ras-Driven Oncogenic Growth
Hair follicle regeneration may slow tumor growth.
research Epidermal Abnormalities and Increased Malignancy of Skin Tumors in Human Epidermal Keratin 8-Expressing Transgenic Mice
Mice with human skin protein K8 had more skin problems and cancer.
research Trends in Human Hair Growth and Alopecia Research
The book reveals diverse patterns of hair growth in different species and advancements in hair and alopecia research.
research Alopecia Universalis in a Dog with Testicular Neoplasia
A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
research Imaging Tumor Angiogenesis with Fluorescent Proteins
Fluorescent proteins in mouse models effectively visualize tumor blood vessel growth.
research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and Pilomatricoma
The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
research Apoptosis in Hair and Skin: A Review
The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
research Hypopigmented Facial Lesions: A Case of Eruptive Tumor of Follicular Infundibulum
Consider TFI in facial hypopigmentation diagnoses and confirm with a biopsy.
research Neoplasms Bypass Immune Evasion via Hair Follicle Residence
Neoplasms hide in hair follicles to avoid the immune system.
research Review of Scalp Alopecia Due to a Clinically Unapparent or Minimally Apparent Neoplasm (SACUMAN)
SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
research Overexpression of Hepatoma-Derived Growth Factor in Melanocytes Does Not Lead to Oncogenic Transformation
Overexpression of HDGF in melanocytes does not cause cancer.
research The Role of Lysophosphatidic Acid in the Physiology and Pathology of the Skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Pilomatricoma With Florid Osseous Metaplasia: A Cytologist’s Perspective
A rare skin tumor with bone formation was successfully removed without recurrence.
research Pilomatrixoma of Face Presenting as Parotid Swelling
A young woman had a rare, usually non-cancerous tumor on her face that was initially mistaken for a different condition.
research Skin Care Properties of Grape Seed Polyphenols, a By-Product of the Winery Industry
Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors
Inactive hair follicle stem cells help prevent skin cancer.
research Panfolliculoma: Report of the Youngest Case and Literature Review of Its Histopathologic Variants
A 14-year-old boy is the youngest person reported with a rare, benign tumor related to hair follicles, usually found in older people.