168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
45 citations,
April 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
3 citations,
August 2020 in “Animals” Researchers found a way to grow cashmere goat hair cells in a lab and discovered that certain conditions improve these cells' growth and characteristics.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
24 citations,
December 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
17 citations,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
15 citations,
October 2006 in “Journal of Cutaneous Pathology” HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
3 citations,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
1 citations,
December 2023 in “Animals” Winter provides the best fur quality for Rex rabbits due to seasonal changes in specific signaling pathways.
19 citations,
July 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
17 citations,
May 2012 in “The Journal of Pathology” In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
1 citations,
January 2013 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
January 2016 in “Elsevier eBooks” The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
68 citations,
April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
December 2022 in “Regenerative Therapy” July 2023 in “Research Square (Research Square)” Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
14 citations,
July 2016 in “Environmental Toxicology and Pharmacology” Cedrol may prevent hair loss caused by chemotherapy better than minoxidil.
301 citations,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
205 citations,
October 2007 in “Experimental Cell Research” Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
March 2024 in “Tissue and cell/Tissue & cell” Telomerase-positive cells are mainly in the bulb matrix and outer root sheath of hair follicles.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
45 citations,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
May 2018 in “International journal of cell science & molecular biology” Early anti-aging hair treatments should focus on anti-inflammatory agents and promoting healthy hair growth cycles.
479 citations,
June 2014 in “Science” Epithelial stem cells can adapt and help in tissue repair and regeneration.
13 citations,
May 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
August 2024 in “Applied Sciences” Plant extracts may help prevent or reverse hair graying.
7 citations,
January 2019 in “PeerJ” A protein called sFRP4 can slow down hair regrowth.
4 citations,
May 2023 in “Pigment Cell & Melanoma Research” BMI1 is essential for preventing hair greying and maintaining hair color.