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Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Improving the environment and cell interactions is key for creating human hair in the lab.

HPV8 causes hair follicle stem cells to grow, leading to skin lesions.

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.

Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

2011 dermatology discussions highlighted stem cell hair treatments, new lichen planopilaris therapies, skin side effects from cancer drugs, emerging allergens, and the link between food allergies and skin issues.

Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

Telocytes, cells with long extensions, are vital for hair growth because they produce Wnt signals, which are necessary for hair follicle regeneration.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.

Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Hair follicles are valuable for regenerative medicine and wound healing.

Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

Artemis dysfunction might cause hair loss through telomere shortening.

Araliadiol may promote hair growth like minoxidil without being toxic.

Dog hair follicle stem cells can turn into fat cells.