242 citations,
February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
June 2023 in “Journal of cosmetic medicine” Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.
March 2022 in “Indian Journal of Animal Research” Dog hair follicle stem cells can turn into fat cells.
17 citations,
May 2014 in “Cell transplantation” Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
12 citations,
July 2020 in “Aging” The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.
35 citations,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
10 citations,
February 2010 in “Acta Histochemica Et Cytochemica” c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.
April 2018 in “Journal of Investigative Dermatology” The research found that a specific skin cell type not only triggers hair growth but also controls hair color, and that aging can lead to hair loss and color changes.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
Skin stem cells in hair follicles are important for touch sensation.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
10 citations,
November 2022 in “Protein & Cell” Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
March 2024 in “Journal of functional foods” Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
51 citations,
November 2010 in “Dermatologic Surgery” The research provides specific measurements for hair follicles that can improve hair transplant and regeneration techniques.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
2 citations,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
April 2018 in “Journal of Investigative Dermatology” Fgf20 is important for the development and regulation of the cells that form the base of hair follicles.
191 citations,
September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
3 citations,
February 2022 in “Frontiers in cell and developmental biology” A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.
Intermittent fasting slows hair growth by damaging hair follicle cells.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
2 citations,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
Ganoderma lucidum extract may help treat stress-related hair loss.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.