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ALRN-6924 may prevent hair loss caused by chemotherapy.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

Higher doses of cranial irradiation are linked to permanent hair loss.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Polymeric nanoparticles show promise for treating skin diseases.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Stem cell self-renewal is complex and needs more research for full understanding.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Macrophage iron release is crucial for hair growth and wound healing.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

Some cancer treatments can cause permanent hair loss.

Foxn1 gene regulation is crucial for thymus development but not for hair growth.

Enzymes called PADIs play a key role in hair growth and loss.

Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Hair shedding after childbirth can reveal a pre-existing condition of hair loss due to tight hairstyles.

Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.