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Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

Cow milk sugars increase fat production and inflammation in skin oil cells.

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

Lymphatic vessels are important for skin repair and could affect skin disease treatments.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

Different types of skin cells play specific roles in development, healing, and cancer.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Fat cells in the skin help start healing and form important repair cells after injury.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Understanding how fetal wounds heal could help improve healing in adults.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.