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Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Cannabidiol shows promise as an effective treatment for acne.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Chicken feather gene mutation helps understand human hair disorders.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Photodynamic Therapy is an effective treatment for mild to severe acne.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Omega-6 and LDL cholesterol increase the risk of hair loss.

More research is needed to understand how testosterone is maintained in adult males.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

A specific protein in chicken embryos links early skin layers to feather development.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.