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Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

Dermal EZH2 controls skin cell growth and differentiation in mice.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

Human sweat glands have a type of stem cell that can grow well and turn into different cell types.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

Different types of stem cells help maintain and heal skin.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

Human dermal stem cells can become functional skin pigment cells.

TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.

Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.

Epidermal stem cells show promise for treating orthopedic injuries and diseases.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.

Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.

The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.