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Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.

ECM1-modified stem cells can effectively treat liver cirrhosis.

Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Hair growth and development are controlled by specific signaling pathways.

Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.

New regenerative treatments for hair loss show promise but need more research for confirmation.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.

Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.

Metabolism plays a key role in determining stem cell fate.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Regenerative cosmetics can improve skin and hair by reducing wrinkles, healing wounds, and promoting hair growth.

Wnt signaling is crucial for skin wound healing and reducing scars.