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    Glossary Hair Follicle Mesenchymal Stem Cells

    cells in hair follicles that can become various tissue types

    Hair Follicle Mesenchymal Stem Cells (HF-MSCs) are a type of stem cell found within the hair follicle that have the ability to differentiate into various cell types, including those that form skin, hair, and connective tissues. These cells play a crucial role in hair growth, wound healing, and tissue regeneration, making them a significant focus in regenerative medicine and treatments for conditions like alopecia.

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    1. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    2. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    3. Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type l Diabetes Cell transplantation · 2014 · 17 citations
    4. A Potential Differentiation of Adipose and Hair Follicle-derived Mesenchymal Stem Cells to Generate Neurons Induced with EGF, FGF, PDGF and Forskolin Research Journal of Pharmacy and Technology · 2020 · 14 citations
    5. Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing Aging · 2023 · 13 citations
    6. The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath Journal of Clinical Medicine · 2021 · 8 citations
    7. The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches JCI Insight · 2023 · 6 citations
    8. Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model Frontiers in Cell and Developmental Biology · 2022 · 6 citations
    9. The role and mechanism of engineered nanovesicles derived from hair follicle mesenchymal stem cells in the treatment of UVB‐induced skin photoaging Journal of Cosmetic Dermatology · 2024 · 5 citations
    10. From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation PeerJ · 2022 · 4 citations
    11. Serum-Free Expanded Hair Follicle Mesenchymal Stem Cells Promote Cartilage Repair in a Murine Full-Thickness Defect Model Transplantation and Cellular Therapy · 2026
    12. Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischaemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model Research Square (Research Square) · 2022
    13. Ficoll density gradient sedimentation isolation of pelage hair follicle mesenchymal stem cells from adult mouse back skin: A novel methods for hair follicle mesenchymal stem cells isolation. Research Square (Research Square) · 2022
    14. Hair Regrowth with Micrografts Enriched with Human Follicle Mesenchymal Stem Cells and Platelet-Rich Plasma Springer eBooks · 2022
    15. Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells Stem Cells and Development · 2006 · 151 citations
    16. Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Re-Growth in Androgenetic Alopecia. Biomolecular Pathway Analysis and Clinical Evaluation Biomedicines · 2019 · 69 citations
    17. A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice Stem Cells International · 2017 · 36 citations
    18. Effects of mesenchymal stem cell therapy on alopecia areata in cellular and hair follicle organ culture models Experimental Dermatology · 2018 · 16 citations
    19. Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles International journal of molecular sciences · 2021 · 14 citations
    20. Hypoxia Mesenchymal Stem Cell-Derived Exosomes (EH-MSCs) enhance IGF-1 and suppress IL-1Beta in hair follicle regeneration DOAJ (DOAJ: Directory of Open Access Journals) · 2026
    21. The Potential of a Hair Follicle Mesenchymal Stem Cell-Conditioned Medium for Wound Healing and Hair Follicle Regeneration Applied sciences · 2020 · 6 citations
    22. OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases Stem Cell Research & Therapy · 2019 · 57 citations
    23. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    24. Mesenchymal stem cell exosomes enhance the development of hair follicle to ameliorate androgenetic alopecia World Journal of Stem Cells · 2025
    25. Hair follicle-derived mesenchymal cells support undifferentiated growth of embryonic stem cells Experimental and Therapeutic Medicine · 2017 · 7 citations
    26. Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system Biochemical and Biophysical Research Communications · 2026
    27. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    28. Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species European Journal of Histochemistry · 2009 · 15 citations
    29. Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles World journal of stem cells · 2022 · 6 citations
    30. Expression of mesenchymal stem cell marker CD90 on dermal sheath cells of the anagen hair follicle in canine species European journal of histochemistry · 2009 · 6 citations